Unité de recherche : UMR_S1050-INSERM UMR7241-CNRS - Collège de France :

Collège de France 
Centre Interdisciplinaire de Recherche en Biologie CIRB
11 place Marcellin Berthelot
75231 PARIS  Cedex 05

Directeur de l'unité de rattachement : : Marie-Hélène VERLHAC

Responsable de l'équipe de recherche :

LLORENS-CORTES Catherine
Courriel : c.llorens-cortesSPAMFILTER@college-de-france.fr	Tel: 01 44 27 16 63

Composition de l'équipe de recherche : :

• BOITARD  Solène (C, Quantum Genomics)
• COMPERE Delphine (C, Quantum Genomics)
• ITURRIOZ Xavier (CR-INSERM, HDR)
• KECK Mathilde (C, Quantum Genomics)
• LLORENS-CORTES Catherine (DR-INSERM, HDR)
• MAIGRET Bernard (DREM-CNRS, HDR)
• MARC Yannick (C, Quantum Genomics)

5 publications récentes et significatives de l'équipe de recherche : :

Central antihypertensive effects of chronic treatment with RB150: an orally active aminopeptidase A inhibitor in deoxycorticosterone acetate-salt rats.Marc Y, Hmazzou R, Balavoine F, Flahault A, Llorens-Cortes C.J Hypertens. 2018 Mar;36(3):641-650. doi: 10.1097/HJH.0000000000001563.

Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues.Couvineau P, de Almeida H, Maigret B, Llorens-Cortes C, Iturrioz X.PLoS One.2017 Sep 6;12(9):e0184237. doi: 10.1371/journal.pone.0184237.

Development of original metabolically stable apelin-17 analogs with diuretic and cardiovascular effects.Gerbier R, Alvear-Perez R, Margathe JF, Flahault A, Couvineau P, Gao J, De Mota N, Dabire H, Li B, Ceraudo E, Hus-Citharel A, Esteoulle L, Bisoo C, Hibert M, Berdeaux A, Iturrioz X, Bonnet D, Llorens-Cortes C.FASEB J. 2017 Feb;31(2):687-700. doi: 10.1096/fj.201600784R.

New structural insights into the apelin receptor: identification of key residues for apelin binding.Gerbier R, Leroux V, Couvineau P, Alvear-Perez R, Maigret B, Llorens-Cortes C, Iturrioz X.FASEB J.2015 Jan;29(1):314-22. doi: 10.1096/fj.14-256339.

Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine.Ceraudo E, Galanth C, Carpentier E, Banegas-Font I, chonegge AM, Alvear-Perez R, Iturrioz X, Bouvier M, Llorens-Cortes C.J Biol Chem. 2014 Aug 29;289(35):24599-610.