GIROS Bruno - DIAZ Jorge : UMR8002 : Pathophysiologie des Maladies Psychiatriques

Unité de recherche : UMR8002 - Université de Paris

Faculté des Sciences Fondamentales et Biomédicales
Integrative Neuroscience and Cognition Center (INCC)
45 rue des Saints-Pères
75270 Paris cedex 06

Spécialité : Biochimie , Biologie moléculaire , Médicament , Neurosciences , Pharmacologie , Transport membranaire

Directeur de l'unité de rattachement : Florian WASZAK

Responsable de l'équipe de recherche :

GIROS Bruno - DIAZ Jorge
Courriel : bruno.girosSPAMFILTER@u-paris.fr Tel: GB 06 14 28 31 37 - DJ 06 66 57 62 69

Composition de l'équipe de recherche :

  • De GOIS Stéphanie (IR)
  • DIAZ Jorge (MC, HDR)
  • GIROS Bruno (PR, HDR)
  • KORNER Marie (DR, HDR)
  • ISINGRINIE lsa (CR)

5 publications récentes de l'équipe de recherche :

Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F,Mechawar N, Williams S, Gratton A, Giros B. Resilience against chronic stress is mediated by
noradrenergic regulation of dopamine neurons. Nature Neuroscience, 2016, 19, 560-563.

Massart R, Mignon V, Stanic J, Tello P, Becker J, Kieffer B. Darmon M. Sokoloff P, J. Diaz.Developmental and adult expression patterns of the G protein coupled receptor GPR88 in the rat: establishment of a dual nuclear-cytoplasmic localization. J. Comp. Neurol. 2016, 524, 2776-802.
Isingrini E, Guinaudie C, Perret LC, Rainer Q, Moquin L, Gratton A, Giros B. Genetic elimination ofdopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson’s disease motor symptoms without neuronal degeneration in adult mice. Scientific Reports, 2017, 7, 12432.

Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP., Grenier J, Ibrahim E, El Khoury M-A,Tse Y.C., Mongredien R, Barbé A, Antunes de Macedo CE, Jaworski W, Bochereau A, Orrico A,Isingrini E, Guinaudie C, Mikasova L, Louis F, Gautron S, Groc L, Massaad C, Yildirim F, Vialou V, Dumas S, Marti F, Mechawar N, Morice E, Wong TP, Caboche J, Turecki G, Giros B*, Tzavara ET*.Antidepressive effects of targeting Elk-1 signal transduction. Nature Medicine, 2018, 24, 591-597. (*:
corresponding authors).

Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch J, Elgbeili G, Courcot B, Mechawar N,Chakravarty MM, Giros B. Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage, 2018, 176, 226-238.