GIROS Bruno - DIAZ Jorge : UMR8002 : PathophysiologiedesMaladiesPsychiatriques

Unité de recherche : UMR8002-CNRS - Université de Paris

Faculté des Sciences Fondamentales et Biomédicales
Integrative Neuroscience and Cognition Center (INCC)
45 rue des Saints-Pères
75270 Paris cedex 06

Spécialité : Biochimie , Biologie moléculaire , Médicament , Neurosciences , Pharmacologie , Pharmacochimie

Directeur de l'unité de rattachement : Florian WASZAK

Responsable de l'équipe de recherche :

GIROS Bruno - DIAZ Jorge
Courriel : bruno.girosSPAMFILTER@u-paris.fr Tel: GB 06 14 28 31 37 - DJ 06 66 57 62 69

Composition de l'équipe de recherche :

  • De GOIS Stéphanie (IR)
  • DIAZ Jorge (MC, HDR)
  • GIROS Bruno (PR, HDR)
  • KORNER Marie (DR, HDR)
  • ISINGRINIE lsa (CR)

5 publications récentes de l'équipe de recherche :

Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP., Grenier J, Ibrahim E, El Khoury M-A, Tse Y.C., Mongredien R, Barbé A, Antunes de Macedo CE, Jaworski W, Bochereau A, Orrico A, Isingrini E, Guinaudie C, Mikasova L, Louis F, Gautron S, Groc L, Massaad C, Yildirim F, Vialou V, Dumas S, Marti F, Mechawar N, Morice E, Wong TP, Caboche J, Turecki G, Giros B*, Tzavara ET*. Antidepressive effects of targeting Elk-1 signal transduction. Nature Medicine, 2018, 24, 591-597. (#: equal participation; *: corresponding authors). PMID: 29736027

Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch J, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage, 2018, 176, 226-238. PMID: 29704613

Ingrini E,Guinaudie C,Perret LC,Rainer Q,Moquin L,Gratton A,Giros B. Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson’s disease motors symptoms without neuronalde generation in adult mice.Scientific Reports,2017,7,12432.

Massart, R., Mignon, V., Stanic, J., Tello, P., Becker, J., Kieffer, B. Darmon, M. Sokoloff, P. and J. Diaz. Developmental and adult expression patterns of the G protein coupled receptor GPR88 in the rat: establishment of a dual nuclear-cytoplasmic localization. J. Comp. Neurol. 2016, 524: 2776-2802.

Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience against chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nature Neuroscience, 2016, 19, 560-563.