Unité de recherche : CEA Fontenay-aux-Roses

CEA Fontenay-aux-Roses
Institut de Radiobiologie Cellulaire et Moléculaire (IRCM)
Service de Radiologie et Innovation Technologique
18 av du Panorama
92265 Fontenay-aux-Roses cedex

Spécialité : Biologie moléculaire , Toxicologie , Biologie cellulaire , Médicament

Directeur de l'unité de rattachement : Sylvie CHEVILLARD

Responsable de l'équipe de recherche :

DELIC Jozo
Courriel : jozo.delicSPAMFILTER@cea.fr	Tel: 01 46 54 81 19

Composition de l'équipe de recherche :

• CHEVILLARD Sylvie (DR, HDR)
• DELIC Jozo (DR, HDR)
• GRALL Romain (CR)
• GOISLARD Maud (IR)
• GUILLY Marie-Noelle (CR)
• LEBEAU Jérôme (DR, HDR)
• MOREL-ALTMEYER Sandrine (IR)
• ORY Cathy (CR)
• UGOLIN Nicolas (CR, HDR)

5 publications récentes et significatives de l'équipe de recherche :

Bouley J, Saad L, Grall R, Schellenbauer A, Biard D, Paget V, Morel-Altmeyer, S, Guipaud O, Chambon C, Salles B, Maloum K, Merle-Béral H, Chevillard 0 and Delic J.  A phosphorylated form of Ku70 confers resistance to chemotherapy in chronic lymphocytic leukemia through fast but unfaithful DNA repair. Oncotarget, 2015, sep29;6(29):27980-8000

Grall, R., Girard, H., Saad, L., Petit, T., Gesset, C., Combis-Schlumberger, M., Paget, V., Delic, J., Arnault, J-C., Chevillard, S. Hydrogenated nanodiamonds combined with g-irradiation drive resistant cancer cells into senescence. Biomaterials, 2015,Aug, 61:290-8

Brugat, T., F. Nguyen-Khac, A. Grelier, H. Merle-Beral, and J. Delic, Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells. Blood, 2010. 116(2): p. 239-49.

Brugat, T., N. Gault, I. Baccelli, J. Maes, A. Roborel de Climens, F. Nguyen-Khac, F. Davi, H. Merle-Beral, E. Gilson, M. Goodhardt, and J. Delic, Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells. Leukemia Research, 2010. 24(1): p. 246-51.

Review Chapter : "DNA Damge Response/Signaling and Genome (In)Stability as the New Reliable Biological Parameters Defining Clinical Feature of CLL". J. Delic, J. Marteau, J-B Maloum, K. Nguyen-Khac, F. Davi, F. Azgui, Z; Leblond, V. Binet, J-L Chevillard, S. Merle-Béral, H. OnLine Book "Chronic Lymphocytic Leukemia", 02/2012