BENICHOU Serge : UMR_S1016 UMR8104 : Virus and Intracellular Trafficking

Unit : INSERM UMR_S1016 CNRS UMR8104 - Institut Cochin -Université Paris Descartes

Institut Cochin
22 rue Méchain
75014 PARIS

Speciality : Department IM

Director of the unit : Pierre-Olivier COURAUD

Principal investigator :

BENICHOU Serge
Email : serge.benichouSPAMFILTER@inserm.fr Phone number: +33 (0)1 40 51 65 78

Composition of research team :

  • BENICHOU Serge (DR1-CNRS, HDR)
  • RODRIGUEZ Manuel (CR1-CNRS, HDR)

5 Recent publications of the research team :

Matz, J., Kessler, P., Bouchet, J., Combes, O., Baty, D., Barin, F., Martin, L., Chames, P.* and S. Benichou* (2013) Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120. J. Virol., 87, 1137-1149. (*equal contribution)

Bouchet, J., Hérate, C., Guenzel, C. Vérollet, C. Järviluoma, A., Mazzolini, J., Rafie, S., Chames, P., Saksela, K., Niedergang, F., Maridonneau-Parini, I. and S. Benichou. (2012) Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions. J. Virol., 86, 4856-4867.

Guenzel, C. A., Hérate, C., Le Rouzic, E., Sadler, H.A., Rouyez, M.-C., Mansky, L.M. and S. Benichou. (2012) Recruitment of the nuclear form of uracil DNA glycosylase into virus particles participates in the full infectivity of HIV-1. J. Virol., 86, 2533-2544.

Bouchet, J., Basmaciogullari, S., Stolp, B., Fackler, O., Chames, P., Baty, D.* and Benichou, S.* (2011) Llama single-domain antibody fragment for inhibition of the Nef regulatory protein of HIV-1. Blood, 117: 3559-3568. (*equal contribution)

Langevin, C., Maidou-Peindara, P., Aas, P.A., Jacquot, G., Otterlei, M., Slupphaug, G. and Benichou S. (2009) HIV-1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect, J. Virol., 83, 10256-10263.