TANGY Frédéric : Institut Pasteur : Viral genomics and Vaccination (CNRS UMR 3569)

Unit : Département de Virologie - Institut Pasteur

Institut Pasteur
Unité de Génomique Virale et Vaccination
28 rue du Docteur Roux
75724 PARIS Cedex 15

Speciality : Department IM

Director of the unit : Felix REY

Principal investigator :

TANGY Frédéric
Email : frederic.tangySPAMFILTER@pasteur.fr Phone number: +33 (0)1 45 68 87 70

Composition of research team :

  • TANGY Frédéric (DR-CNRS, HDR)
  • ESCRIOU  Nicolas (CR-IP)
  • KOMAROVA Anastasia (CR-IP)
  • JOUVENET Nolwenn (CR-CNRS, HDR)

5 Recent publications of the research team :

Ramsauer K, Schwameis M, Firbas C, Müllner M, Putnak RJ, Thomas SJ, Desprès P, Tauber E, Jilma B, Tangy F. (2015). Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial. Lancet Infect Dis. 2015 Feb 27. pii: S1473-3099(15)70043-5. doi: 10.1016/S1473-3099(15)70043-5.

Bruni D, Chazal M, Sinigaglia L, Chauveau L, Schwartz O, Desprès P, Jouvenet N. (2015). Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons. Sci Signal. 2015 Mar 3;8(366):ra25. doi: 10.1126/scisignal.aaa1552.

Vabret N, Bailly-Bechet M, Lepelley A, Najburg V, Schwartz O, Verrier B, Tangy F. (2014). Large-scale nucleotide optimization of simian immunodeficiency virus (SIV) reduces its capacity to stimulate type-I IFN in vitro. J Virol. 2014 88(8):4161-72.

Lucas-Hourani M, Dauzonne D, Jorda P, Cousin G, Lupan A, Helynck O, Caignard G, Janvier G, André-Leroux G, Khiar S, Escriou N, Desprès P, Jacob Y, Munier-Lehmann H, Tangy F, Vidalain PO. (2013). Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity. PLoS Pathog. 2013 Oct;9(10):e1003678. doi: 10.1371/journal.ppat.1003678. Epub 2013 Oct 3.

Stebbings R, Li B, Lorin C, Koutsoukos M, Février M, Mee ET, Page M, Almond N, Tangy F, Voss G. (2014). Immunogenicity of a recombinant measles HIV-1 subtype C vaccine. Vaccine. 2013 Oct 24. doi:pii: S0264-410X(13)01356-X. 10.1016/j.vaccine.2013.09.072.