ARENZANA Fernando : Institut Pasteur : Viral Pathogenesis Unit

Unit : Département de Virologie - Institut Pasteur

Institut Pasteur
Département de Virologie (Unité de Pathogénie Virale)
25-28 rue du Dr. Roux
75015 PARIS

Speciality : Department IM

Director of the unit : Olivier SCHWARTZ

Principal investigator :

ARENZANA Fernando
Email : farenzanSPAMFILTER@pasteur.fr Phone number: +33 (0)1 45 68 82 63

Composition of research team :

  • ARENZANA Fernando  (DR1 INSERM/CL-IP, HDR)
  • CHAKRABARTI Lisa (CL-IP, HDR)    
  • LAGANE Bernard (CR1-INSERM, HDR)
  • BRELOT Anne (CR1-INSERM, HDR)
  • STAROPOLI Isabelle (Ingénieur IP) 

5 Recent publications of the research team :

Colin P, Benureau Y, Staropoli I, Wang YJ, Gonzalez N, et al. (2013) HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines. Proceedings of the National Academy of Sciences of the United States of America 110: 9475-9480.

Rueda P, Richart A, Recalde A, Gasse P, Vilar J, et al. (2012) Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions. Circulation 126: 1882-U1262.

Vingert B, Benati D, Lambotte O, de Truchis P, Slama L, Jeannin P, Galperin M, Perez-Patrigeon S, Boufassa F, Kwok WW, Lemaître F, Delfraissy JF, Thèze J, Chakrabarti LA. HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.J Virol. 2012 Oct;86(19):10661-74.

Garcia-Perez J, Rueda P, Alcami J, Rognan D, Arenzana-Seisdedos F, et al. (2011) Allosteric Model of Maraviroc Binding to CC Chemokine Receptor 5 (CCR5). Journal of Biological Chemistry 286: 33409-33421.Garcia-Perez J, Rueda P, Staropoli I, Kellenberger E, Alcami J, et al. (2011) New Insights into the Mechanisms whereby Low Molecular Weight CCR5 Ligands Inhibit HIV-1 Infection. Journal of Biological Chemistry 286: 4978-4990.