ROUAS-FREISS Nathalie : UMR CEA_UP7 : Transplantation Immunology Laboratory

Unit : UMR_CEA Université Paris Diderot -

Laboratoire d'Immunologie de la Transplantation
CEA Direction des Sciences du Vivant
Institut des Maladies Emergentes et des Thérapies Innovantes
Service de Recherche en Hémato-Immunologie
Hôpital Saint-Louis
1 avenue Claude Vellefaux
75010 PARIS

Speciality : Department IMMUNO

Director of the unit : Edgardo CAROSELLA

Principal investigator :

ROUAS-FREISS Nathalie
Email : nathalie.rouas-freissSPAMFILTER@cea.fr Phone number: +33 (0)1 57 27 68 01

Composition of research team :

  • ROUAS-FREISS Nathalie (Chef de laboratoire,HDR)
  • MOREAU Philippe (Chef d’équipe, HDR) 

5 Recent publications of the research team :

Naji A., Menier C., Maki G., Carosella E.D., Rouas-Freiss N.(2012 Aug). Neoplastic B cell growth is impaired by HLA-G/ILT2 interaction. Leukemia, (2012) (8):1889-92.

Agaugue S., Carosella E.D., Rouas-Freiss N.(2011 Jun) Role of HLA-G in tumor escape through expansion of myeloid-derived suppressor cells and cytokinic balance in favor of Th2 vs Th1/Th17. Blood, 30;117(26):7021-31.

Brugière O., Thabut G., Pretolani M., Krawice-Radanne I., Dill C., Herbreteau A., Poras I., Moreau P., Colombat M., Danel C., Dehoux M., Carosella E.D., Rouas-Freiss N. (2009) Immunohistochemical study of HLA-G expression in lung transplant recipients. Am. J. Transpl., 9:1427-1438.

Carosella E.D., Moreau P., LeMaoult J., Rouas-Freiss N.(2008). HLA G: from biology to clinical benefits. Trends in Immunology. 29:125-132.

Naji A., Le Rond S., Durrbach A., Krawice-Radanne I., Creput C., Daouya M., Caumartin J., LeMaoult J., Carosella E.D., and Rouas-Freiss N. (2007). CD3+CD4low and CD3+CD8low are induced by HLA-G: novel human peripheral blood suppressor T cell subsets involved in transplant acceptance. Blood, 110:3936-3948