RAPOSO Graça : UMR 144 : Structure and Membrane Compartments

Unit : CNRS UMR 144 Compartimentation et Dynamiques cellulaires - Institut Curie

Institut Curie
CNRS UMR 144 "Compartimentation et Dynamiques Cellulaires"
Laboratoires Constant Burg
26 rue d'Ulm
75248 PARIS Cedex 05

Speciality : Department BCMPP

Director of the unit : Bruno GOUD (Directeur) et Graça RAPOSO (Directrice adjointe)

Principal investigator :

RAPOSO Graça
Email : graca.raposoSPAMFILTER@curie.fr Phone number: +33 (0)1 56 24 64 41

Composition of research team :

  • RAPOSO Graça (DR1 CNRS, HDR)
  • van NIEL Guillaume (CR1 CNRS, HDR)
  • DELEVOYE Cédric (CR1 INSERM)
  • HURBAIN Ilse (IR2 CNRS)
  • ROMAO Maryse (IR2 Institut Curie)
  • BERGAM Ptissam (IE2 CNRS)

5 Recent publications of the research team :

1: Delevoye C, Miserey-Lenkei S, Montagnac G, Gilles-Marsens F, Paul-Gilloteaux P, Giordano F, Waharte F, Marks MS, Goud B, Raposo G. Recycling endosome tubule morphogenesis from sorting endosomes requires the kinesin motor KIF13A. Cell Rep. 2014

2: Colombo M, Moita C, van Niel G, Kowal J, Vigneron J, Benaroch P, Manel N, Moita LF, Théry C, Raposo G. Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci. 2013

3: Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013 Feb 18;200(4):373-83. doi: 10.1083/jcb.201211138. Review. PubMed PMID: 23420871; PubMed Central PMCID: PMC3575529. 

4: van Niel G, Charrin S, Simoes S, Romao M, Rochin L, Saftig P, Marks MS, Rubinstein E, Raposo G. The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell. 2011

5: Giordano F, Simoes S, Raposo G. The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for  transport (ESCRT) function. Proc Natl Acad Sci U S A. 2011