KELLERMANN Odile et SCHNEIDER Benoît : UMR_S1124 : Stem cells, Signaling and Prions

Unit : INSERM UMR_S1124 "Toxicologie, Pharmacologie et Signalisation Cellulaire" - Université Paris descartes

Université Paris Descartes
Faculté des Sciences Fondamentales et Biomédicales
INSERM UMR_S1124  "Toxicologie, Pharmacologie et Signalisation Cellulaire"
Equipe "Cellules souches, signalisation et prions"
45 rue des Saints Pères
75270 PARIS cedex 06

Speciality : Department DGNRV

Director of the unit : Robert BAROUKI

Principal investigator :

KELLERMANN Odile et SCHNEIDER Benoît
Email : odile.kellermannSPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 42 86 20 65 (O. KELLERMANN) - +33 (0)1 42 86 22 09 (B. SCHNEIDER)

Composition of research team :

  • KELLERMANN Odile (PR, HDR)
  • SCHNEIDER Benoit (CR-CNRS, HDR) 
  • BAUDRY Anne (CR-INSERM) 
  • PIETRI Mathéa (MCF) 
  • GOLDBERG Michel (PR, Emerite)

5 Recent publications of the research team :

Alleaume-Butaux A, Nicot S, Pietri M, Baudry A, Dakowski C, Tixador P, Ardila-Osorio H, Haeberlé AM, Bailly Y, Peyrin JM, Launay JM, Kellermann O, Schneider B. Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation.PLoS Pathog. 2015; 11(8):e1005073. 

Baudry A, Alleaume-Butaux A, Dimitrova-Nakov S, Goldberg M, Schneider B, Launay JM, Kellermann O. Essential Roles of Dopamine and Serotonin in Tooth Repair: Functional Interplay Between Odontogenic Stem Cells and Platelets. Stem Cells. 2015;33(8):2586-95.

Pietri M, Dakowski C, Hannaoui S, Alleaume-Butaux A, Hernandez-Rapp J, Ragagnin A, Mouillet-Richard S, Haik S, Bailly Y, Peyrin JM, Launay JM, Kellermann O, Schneider B. PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases. Nat Med. 2013;19(9):1124-31.

Loubet D, Dakowski C, Pietri M, Pradines E, Bernard S, Callebert J, Ardila-Osorio H, Mouillet-Richard S, Launay JM, Kellermann O, Schneider B. Neuritogenesis: the prion protein controls β1 integrin signaling activity. FASEB J. 2012; 26(2):678-90.

Baudry A, Mouillet-Richard S, Schneider B, Launay JM, Kellermann O. miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science. 2010; 329(5998):1537-41.