LENNON-DUMENIL Ana-Maria : Institut Curie : Spatio-temporal Regulation of Antigen Presentation and Cell Migration

Unit : INSERM UMR_S932 "Immunité et Cancer" Insttut Curie/Université Paris Descartes

Institut Curie
INSERM UMR_S932 « Immunité et cancer »
12 rue Lhomond
75005 PARIS

Speciality : Department IMMUNO

Director of the unit : Sebastian AMIGORENA

Principal investigator :

LENNON-DUMENIL Ana-Maria
Email : Phone number:

Composition of research team :

  • LENNON-DUMENIL Ana-Maria (CL, HDR)      
  • PIEROBON Paolo (CR1-CNRS)       
  • MALBEC Odile (IGR-INSERM)

5 Recent publications of the research team :

Yuseff MI, Reversat A, Pierobon P and Lennon-Dumenil AM. Shaping B cell responses thrugh cell polarity. Nat Rev Immunol. (2013) 13(7):475

Moreau HD, Lemaître F, Terriac E, Azar G, Piel M, Lennon-Dumenil AM, Bousso P.. Dynamic in situ cytometry uncovers T cell receptor signaling during immunological synapses and kinapses in vivo. Immunity (2012) 37(2):351-63.

Yuseff MI, Reversat A, Lankar D, Diaz J, Fanget I, Pierobon P, Randrian V, Larochette N, Vascotto F, Desdouets C, Jauffred B, Bellaiche Y, Gasman S, Darchen F, Desnos C and  Lennon-Duménil AM. Polarized Secretion of Lysosomes at the B Cell Synapse Couples Antigen Extraction to Processing and Presentation. Immunity (2011) 35(3):361-74.

Jacobelli J, Friedman RS, Conti MA, Lennon-Duménil AM, Piel M, Sorensen MC,Adelstein RS and Krummel MF. Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions. Nature Immunology (2010) 11: 953.

Faure-André G, Vargas P, Yuseff MI, Heuzé M, Diaz J, Lankar D, Steri V, Manry J,

Hugues S, Vascotto F, Boulanger J, Raposo G, Bono MR, Rosemblatt M, Piel M and

Lennon-Duménil AM. Regulation of Dendritic Cell Migration by CD74, the MHC class II associated Invariant Chain. Science (2008) 322(5908):1705.