BLANK Ulrich & LAUNAY Pierre : UMR_S1149 CNRS ERL8252 : Role of Mast and Basophils in Inflammation and Remodeling

Unit : UMR_S1149 CNRS ERL8252 Centre de Recherche sur l'Inflammation (CRI) Université Paris Diderot

Centre de Recherche sur l'Inflammation (CRI)
Faculté de Médecine - Site Xavier Bichat
16 rue Henri Huchard
75870 PARIS Cedex 18

Speciality : Department IMMUNO

Director of the unit : Renato MONTEIRO

Principal investigator :

BLANK Ulrich & LAUNAY Pierre
Email : ulrich.blankSPAMFILTER@inserm.fr Phone number: +33 (0)1 57 27 73 45 (U. BLANK) +33 (0)1 57 27 73 45 (P. LAUNAY)

Composition of research team :

  • BLANK  Ulrich  (DR-CNRS, HDR) 
  • LAUNAY Pierre (DR-INSERM, HDR)
  • BENHAMOU Marc (CR-INSERM, HDR) 
  • CHARLES Nicolas (CR-INSERM, HDR) 
  • DAUGAS Eric (PUPH, HDR)  
  • EL-GHONEIMI  Alaa (PUPH, HDR)  
  • GAUTIER Gregory (MCF) 
  • PAPO Thomas (PUPH, HDR) 
  • SACRE  Karim (PHU, HDR)

5 Recent publications of the research team :

Beghdadi W, Madjene LC, Claver J, Pejler G., Beaudoin L, Lehuen A, Daugas E, Blank U. (2013). Murine mast-cell chymase (mMCP4) protects against renal fibrosis in unilateral ureteral obstruction. Kidney Int.; 84:317-26.

Serafini N, Dahdah A, Barbet G, Demion M, Attout T, Gautier G, Arcos-Fajardo M, Souchet H, Jouvin MH, Vrtovsnik F, Kinet JP, Benhamou M, Monteiro RC, Launay P.(2012). The TRPM4 channel controls monocyte and macrophage, but not neutrophil, function for survival in sepsis. J Immunol.;189(7):3689-99. (IF = 5.75).

Pfirsch-Maisonnas S, Aloulou M, Xu T, Claver J, Kanamaru Y, Tiwari M, Launay P, Monteiro RC, Blank U. (2011). Inhibitory ITAM signaling traps activating receptors with the phosphatase SHP-1 to form polarized "inhibisome" clusters. Sci Signal; 4:ra24 (IF=6.12).

Scandiuzzi L, Beghdadi W, Daugas E, Abrink M, Tiwari N, Brochetta C, Claver J, Arouche N, Zang X, Pretolani M, Monteiro RC, Pejler G, Blank U. (2010). Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis. J Immunol; 185:624-33. (IF=5.75).

Charles, N., Hardwick, D., Daugas, E., Illei, G.G., Rivera, J. (2010).Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat; 16:701-07 (IF = 25.43).