MARULLO Stefano : UMR_S1016 - UMR8104 : Receptor Signaling and Molecular Scaffolds

Unit : INSERM UMR_S1016 CNRS 8104 - Institut Cochin - Université Paris Descartes

Institut Cochin INSERM UMR_S1016 CNRS 8104
Equipe "Signalisation des récepteurs et complexes moléculaires"
22 rue Méchain
75014 PARIS

Speciality : Department BCMPP

Director of the unit : Pierre Olivier COURAUD

Principal investigator :

MARULLO Stefano
Email : stefano.marulloSPAMFILTER@inserm.fr Phone number: +33 (0)1 40 51 65 52

Composition of research team :

  • MARULLO Stefano (DR1-INSERMn HDR)
  • ENSLEN Hervé (CR1-INSERM, HDR)
  • SCOTT Mark (CR1-CNRS, HDR)

5 Recent publications of the research team :

Lima-Fernandes E, Enslen H, Camand E, Kotelevets L, Boularan C, Achour L, Benmerah A,  Gibson L, Baillie GS,  Pitcher JA, Chastre E, Etienne-Manneville S, Marullo S and Scott MGH. Distinct unctional outputs of PTEN signaling are controlled by dynamic association with b-arrestins. EMBO J. 30:2557-2568 (2011).

Coureuil M., Lécuyer H., Scott M.G.H., Boularan C., Enslen H., Soyer M., Mikaty G.,Bourdoulous S., Nassif X. and Marullo S. Meningococcus hijack a b2-adrenoceptor-b-arrestin pathway to cross brain microvasculature endothelium. Cell 143:1149-1160 (2010).

Bourougaa K, Naski N, Boularan C, Mlynarczyk, Candeias MM, Marullo S, and Fåhraeus R. Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47. Mol Cell 38:78-88 (2010).

Achour L, Scott MGH, Shirvani H, Thuret A, Bismuth G, Labbé-Jullié C and Marullo S. CD4 - CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface. Blood 113:1938-1947 (2009).

Boularan C, Scott MG, Bourougaa K, Bellal M, Esteve E, Thuret A, Benmerah A, Tramier M, Coppey-Moisan M, Labbé-Jullié C, Fåhraeus R and Marullo S. Beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53. Proc Natl Acad Sci USA 104:18061-18066 (2007).