ESTAQUIER Jérôme : FR3636 : Programmed Cell Death and Cell Signaling

Unit : CNRS FR3636 Mort cellulaire programmée et signalisation - Université Paris Descartes

Faculté des Sciences Fondamentales et Expérimentales
CNRS FR3636 "Mort cellulaire programmée et signalisation"
45 rue des Saints Pères
75006 PARIS

Speciality : Department IM

Director of the unit : Daniel ZYTNICKI

Principal investigator :

ESTAQUIER Jérôme
Email : jerome.estaquierSPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 42 86 41 36/38

Composition of research team :

  • Estaquier Jérôme, DR2 INSERM, HDR
  • Krust Bernard, CR1 INSERM, HDR
  • Laforge Mireille, contractuelle, HDR

5 Recent publications of the research team :

Rodrigues V, Laforge M, Campillo-Gimenez L, Soundaramourty C, Correia-de-Oliveira A, Dinis-Oliveira RJ, Ouaissi A, Cordeiro-da-Silva A, Silvestre R, Estaquier J. Abortive T follicular helper development is associated with a defective humoral response in Leishmania infantum-infected macaques. PLoS Pathog. 2014. 10:e1004096.

Laforge M, Limou S, Harper F, Casartelli N, Rodrigues V, Silvestre R, Haloui H, Zagury JF, Senik A, Estaquier J. 2013. DRAM triggers Lysosomal Membrane Permeabilization and Cell Death in CD4(+) T Cells Infected with HIV.  PLoS Pathog. 9: e1003328.

Laforge M, Campillo-Gimenez L, Monceaux V, Cumont MC, Hurtrel B, Corbeil J, Zaunders J, Elbim C, Estaquier J. 2011. HIV/SIV infection primes monocytes and dendritic cells for apoptosis. PLoS Pathog. 7(6):e1002087.

Campillo-Gimenez L, Cumont MC, Fay M, Kared H, Monceaux V, Diop O, Müller-Trutwin M, Hurtrel B, Lévy Y, Zaunders J, Dy M, Leite-de-Moraes MC, Elbim C, Estaquier J. 2010. AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection. J Immunol. 184: 984-992.

Campillo-Gimenez L, Laforge M, Fay M, Brussel A, Cumont MC, Monceaux V, Diop O, Lévy Y, Hurtrel B, Zaunders J, Corbeil J, Elbim C, and Estaquier J. 2009. Non pathogenesis of SIV infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase. J Virol. 84 : 1838-1846.