ELADARI Dominique : UMR_S970 : Pathophysiology of the Renal Tubule, Homeostasie and Blood Pressure

Unit : INSERM UMR_S970 Paris-Centre de Recherche Cardiovasculaire Université Paris Descartes

Paris Centre de Recherche Cardiovasculaire (PARCC)
Equipe "Pathophysiology of the Renal Tubule, Homeostasie and Blood Pressure"
Hôpital Européen Georges Pompidou
56 rue Leblanc
75737 PARIS Cedex 15

Speciality : Department BCMPP

Director of the unit : Alain TEDGUI

Principal investigator :

ELADARI Dominique
Email : dominique.eladariSPAMFILTER@inserm.fr Phone number: +33 (0)6 15 32 29 45

Composition of research team :

  • ELADARI  Dominique (MCU-PH, HDR) 
  • CHAMBREY Régine (CR1-CNRS)  
  • HADCHOUEL  Juliette (CR1-INSERM, HDR)

5 Recent publications of the research team :

Gueutin V, Vallet M, Jayat M, Peti-Peterdi J, Cornière N, Leviel F, Sohet F, Wagner CA, Eladari D, Chambrey R. (2013 Sep 24). Renal β-intercalated cells maintain body fluid and electrolyte balance. J Clin Invest. doi:pii: 63492. 10.1172/JCI63492. [Epub ahead of print]

Vidal-Petiot E, Elvira-Matelot E, Mutig K, Soukaseum C, Baudrie V, Wu S, Cheval L, Huc E, Cambillau M, Bachmann S, Doucet A, Jeunemaitre X, Hadchouel J. (2013 Aug 27). WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron. Proc Natl Acad Sci U S A.;110(35):14366-71. doi: 10.1073/pnas.1304230110. Epub 2013 Aug 12.

Chambrey R, Kurth I, Peti-Peterdi J, Houillier P, Purkerson JM, Leviel F, Hentschke M, Zdebik AA, Schwartz GJ, Hübner CA, Eladari D.(Epub 2013 Apr 22.). Renal intercalated cells are rather energized by a proton than a sodium pump. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7928-33. doi: 10.1073/pnas.1221496110.

Vidal-Petiot E, Cheval L, Faugeroux J, Malard T, Doucet A, Jeunemaitre X, Hadchouel J. (2012). A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms. PLoS One. 7(5):e37751. Doi: 10.1371/journal.pone.0037751. Epub 2012 May 31.

Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, Hummler E, Shull GE, Aronson PS, Doucet A, Wall SM, Chambrey R, Eladari D. (2010 May). The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. J Clin Invest.;120(5):1627-35. doi: 10.1172/JCI40145. Epub 2010 Apr 12.