HOUILLIER Pascal : UMR_S1138 : Pathophysiology of electrolyte transport in the Kidney

Unit : INSERM UMR_S1138 - Centre de Recherche des Cordeliers

Centre de Recherche des Cordeliers INSERM UMR_S1138
"Métabolisme et physiologie rénale" CNRS ERL8228
15 rue de l'Ecole de Médecine
75006 PARIS

Speciality : Department BCMPP

Director of the unit : Pascal FERRE

Principal investigator :

HOUILLIER Pascal
Email : pascal.houillierSPAMFILTER@inserm.fr Phone number: +33 (0)1 56 09 39 72/ +33 (0)1 44 27 50 11

Composition of research team :

  • HOUILLIER Pascal (PU-PH, HDR)    
  • PLANELLE Gabrielle (DR-INSERM, HDR)
  • CRAMBERT Gilles (CR1-CNRS, HDR)

5 Recent publications of the research team :

Tokonami N, Morla L, Centeno G, Mordasini D, Ramakrishnan SK, Nikolaeva S, Wagner CA, Bonny O, Houillier P, Doucet A, Firsov D. α-Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism. J. Clin. Invest. 2013 123(7):3166-71

BAKOUH N, CHERIF-ZAHAR B, HULIN P, PRIE D, FRIEDLANDER G, EDELMAN A, PLANELLES G. Functional interaction between CFTR and the sodium-phosphate co-transport type 2a in Xenopus laevis oocytes. PLoSONE 7(4):e34879. 2012

HAMDAOUI N, BAUDOIN-LEGROS M, KELLY M, AISSAT A, MORICEAU S, VIEU DL, COLAS J, FRITSCH J, EDELMAN A, PLANELLES G.  Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1. Br J Pharmacol.163(4):876-86. 2011

Loupy A., Ramakrishnan S.K., Wootla B., Chambrey R., de la Faille R., Bourgeois S., Bruneval P., Mandet C., Christensen E.I., Faure H., Cheval L., Laghmani K., Collet C., Eladari D., Dodd R.H., Ruat M., Houillier P. PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor in rats. J. Clin. Invest. 2012 Sep 4;122(9):3355-67

Bourgeois S, Meer LV, Wootla B, Bloch-Faure M, Chambrey R, Shull GE, Gawenis LR, Houillier P. NHE4 is critical for the renal handling of ammonia in rodents. J Clin Invest 120: 1895-1904, 2010 (16.6)