FOURNIER Thierry : UMR_S1139 : Pathophysiology and Pharmacotoxicoloty of the Human placenta / Microbiote Pré & Postnatal

Unit : INSERM UMR_S1139

Faculté des Sciences Pharmaceutiques et Biologiques
INSERM UMR_S1139
4 avenue de l'Observatoire
75006 PARIS

Speciality : Department DGNRV

Director of the unit : Thierry FOURNIER

Principal investigator :

FOURNIER Thierry
Email : thierry.fournierSPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 53 73 96 00

Composition of research team :

Thierry Fournier (DR2, Inserm, HDR)

Sophie Gil (Pr, HDR)

Katell Peoch (MCUPH, Biologiste, HDR)           

Vassilis Tsatsaris (PUPH, Obstétricien, HDR)

Jean-Louis Beaudeux (PUPH, Biologiste, HDR)

Pierre François Ceccaldi (MCUPH, Obstétricien, HDR)

Jean Guiburdenche (PUPH, Biologiste, HDR)

Christelle Laguillier (MCUPH, Biologiste)

Ioana Parvu-Ferecatu (MCF)

Amal Zerrad-Saadi (MCF)

Nathalie Eilstein (MCF)

5 Recent publications of the research team :

Fournier T, Guibourdenche J, Evain-Brion D. Review: hCGs: different sources of production, different glycoforms and functions. Placenta. 2015;36 Suppl 1:S60-5.

Berveiller P, Degrelle SA, Segond N, Cohen H, Evain-Brion D, Gil S. Drug transporter expression during in vitro differentiation of first-trimester and term human villous trophoblasts. Placenta. 2015;36:93-6.

Segond N, Degrelle SA, Berndt S, Clouqueur E, Rouault C, Saubamea B, Dessen P, Fong KS, Csiszar K, Badet J, Evain-Brion D, Fournier T. Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.PLoS One. 2013;8:e79413.

Berndt S, Blacher S, Munaut C, Detilleux J, Perrier d'Hauterive S, Huhtaniemi I, Evain-Brion D, Noël A, Fournier T*, Foidart JM*. *equally contributed. Hyperglycosylated human chorionic gonadotropin stimulates angiogenesis through TGF-β receptor activation. FASEB J. 2013 Apr;27(4):1309-21.

Lecarpentier E, Cordier AG, Proulx F, Fouron JC, Gitz L, Grange G, Benachi A, Tsatsaris V. Hemodynamic impact of absent or reverse end-diastolic flow in the two umbilical arteries in growth-restricted fetuses. PLoS One. 2013;8:e81160.