BALDACCI Giuseppe : UMR7592 : Pathology of DNA replication

Unit : CNRS UMR7592 - Institut Jacques Monod - Université Paris Diderot

Institut Jacques Monod - CNRS UMR7592
Université Paris Diderot
15 rue Hélène Brion
75013 PARIS

Speciality : Department DGNRV

Director of the unit : Giuseppe BALDACCI

Principal investigator :

BALDACCI Giuseppe
Email : baldacci.giuseppeSPAMFILTER@ijm.univ-paris-diderot.fr Phone number: +33 (0)1 57 27 81 39

Composition of research team :

  • BALDACCI Giuseppe (PR, HDR)
  • CADORET Jean-Charles (MCU)
  • FAUCHEREAU Fabien (MCU)
  • HAENNI Anne-Lise (DR-CNRS, Emérite)
  • MARIC Chrystelle (CR1-CNRS)

5 Recent publications of the research team :

A role for DNA Polymerase Theta in the timing of DNA replication. Fernandez-Vidal A*, Guitton-Sert L*, Cadoret JC*, Drac M, Schwob E, Baldacci G, Cazaux C, Hoffman JS. Nature Commun. 2014 Jul 3 ;5 :4285.

USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator. Hassan-Zadeh V#, Chilaka S#, Cadoret JC, Ma MK, Boggetto N, West AG, Prioleau MN. PLoS Biol. (2012) 10:e1001277.

Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in distinct language-related regions. Pinel P, Fauchereau F, Moreno A, Barbot A, Lathrop M, Zelenika D, Le Bihan D, Poline JB, Bourgeron T, Dehaene S. J Neurosci. (2012) 32:817-25.

Single-stranded DNA binding proteins unwind the newly synthesized double-stranded DNA of model miniforks. Delagoutte E, Heneman-Masurel A, Baldacci G. Biochemistry. (2011) 50:932-44.

Homologous recombination restarts blocked replication forks  at the expense of genome rearrangements by template exchange. Lambert S, Mizuno K, Blaisonneau J, Martineau S, Chanet R, Fréon K, Murray JM, Carr AM, Baldacci G. Mol Cell. (2010) 39:346-59.