LARUE Lionel : U1021 – UMR3347 : Normal and Pathological Development of Melanocytes

Unit : INSERM U1021 CNRS UMR3347 - Institut Curie Univeristé Paris 11

Institut Curie
INSERM U1021 CNRS UMR3347  Signalisation normale et pathologique : de l'embryon aux thérapies innovantes des cancers
Bâtiment 110
Centre Universitaire
91405 ORSAY Cedex

Speciality : Department DGNRV

Director of the unit : Simon SAULE (Directeur) et Lionel LARUE (Directeur Adjoint)

Principal investigator :

LARUE Lionel
Email : lionel.larueSPAMFILTER@curie.fr Phone number: +33 (0)1 69 86 71 07

Composition of research team :

  • LARUE Lionel (DR-INSERM, HDR)
  • BONAVENTURE Jacky (DR-CNRS, HDR)
  • DELMAS Véronique (DR-CNRS, HDR)
  • GESBERT Franck (MCU, HDR)

 

5 Recent publications of the research team :

Gallagher, S.J*, Rambow, F*, Kumasaka, M*, Champeval, D., Bellacosa, A., Delmas, V. and Larue, L. (2013). Beta-catenin inhibits melanocyte migration but induces melanoma metastasis. Oncogene 32, 2230-2238. PMID:22665063.

Berlin, I., Denat, L., Steunou, A.L., Puig, I., Champeval, D., Goodall, J., Bonvin, E., Bourgeois, Y., Delmas, V., Davidson, I., Nieto, L., Goding, C.R. and Larue, L.(2012). Brn-2 affects proliferation of melanocyte lineage during mouse development. Mol Cell Biol. 32:1237-47. PMID:22290434

Luciani, F., Champeval, D., Herbette, A., Denat, L., Aylaj, B., Martinozzi, M., Ballotti, R., Kemler, R., Goding, C.R., De Vuyst, F., Larue, L.* & Delmas, V.* (2011). Biological and Mathematical Modeling of Melanocyte Development.  Development (2011) 138, 3943-3954. PMID:21862558 *Co-last authors. PMID:21862558

Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D., Bartolomei, M., Rambow, F., Bassi, M.R., Bruno, T., Fanciulli, M., Renner, C., Klein-Szanto, A.J., Matsumoto, Y., Kobi, D., Davidson, I., Alberti, C., Larue L. and Bellacosa, A. (2011) DNA demethylation and protection from hypermethylation by TDG in mammalian development. Cell 146:67-79. PMID:21722948.