ROUGEULLE Claire : UMR7216 : Non-coding RNAs, Differenciation and Development

Unit : CNRS UMR7216 "Epigénétique et Destin Cellulaire" Université Paris Diderot

Université Paris Diderot
CNRS UMR7216 Epigénétique et Destin Cellulaire
Bâtiment Lamarck
case 7042
35 rue Hélène Brion
75205 PARIS Cedex 13

Speciality : Department DGNRV

Director of the unit : Jonathan WEITZMAN

Principal investigator :

Email : Phone number: +33 (0)1 57 27 89 29

Composition of research team :

  • MOREY Céline (CR1-INSERM)
  • VALLOT Céline (CR2-CNRS)
  • OUIMETTE Jean-François (MCU-Paris Diderot)
  • HURET Christophe (IE Paris Diderot)

5 Recent publications of the research team :

Vallot* C., Ouimette* JF., Makhlouf M., Féraud O., Pontis J. Côme J., Martinat C., Bennaceur-Griscelli A., Lalande M. and Rougeulle C. (2015) Erosion of X chromosome inactivation in human pluripotent cells initiates with XACT coating and depends on a specific heterochromatin landscape. Cell Stem Cell. 16: 533-46.

Makhlouf* M., Ouimette* JF., Oldfield* A., Navarro P., Neuillet D. and Rougeulle C. (2014) A prominent and conserved role for YY1 in Xist transcriptional activation. Nature Com. 5, 4878. 

Vallot C. and Rougeulle C. (2013) Long non-coding RNAs and human X-chromosome regulation: A coat for the active X chromosome. RNA Biology, 10: 1262-1265.

Vallot C., Huret C., Lesecque Y., Resch A., Oudrhiri N., Bennaceur-Griscelli A., Duret L. and Rougeulle C. (2013) XACT, a long non-coding transcript coating the active X chromosome in human pluripotent cells. Nature Genet. 45:239-41. Epub Jan 20.

Chureau C., Chantalat S., Romito A., Galvani A., Duret L., Avner P. and Rougeulle C. (2011) Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Hum. Mol. Genet., 20: 705-718.