GICQUEL Brigitte : Institut Pasteur : Mycobacterial Genetics Unit

Unit : Département Génomes et Génétique - Institut Pasteur

Institut Pasteur
Département Génomes et Génétiques
25-28 rue du Dr. Roux
75015 PARIS

Speciality : Department IM

Director of the unit : Didier MAZEL

Principal investigator :

GICQUEL Brigitte
Email : bgicquelSPAMFILTER@pasteur.fr Phone number: +33 (0)1 44 38 91 53

Composition of research team :

  • GICQUEL Brigitte (PR-IP, HDR)
  • TAILLEUX Ludovic (CR)
  • PIERRE-AUDIGER Catherine (médecin)

5 Recent publications of the research team :

Namouchi A, Didelot X, Schöck U, Gicquel B, Rocha EP. After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection. Genome Res. 2012 Apr;22(4):721-34.

Barreiro LB, Tailleux L, Pai AA, Gicquel B, Marioni JC, Gilad Y. Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA. 2012 Jan 24;109(4):1204-9

Brodin P, Poquet Y, Levillain F, Peguillet I, Larrouy-Maummus G, Gilleron M, Ewann F, Christophe T, Fenistein D, Jang J, Jang MS, Park SJ, Rauzier J, Carralot JP, Shrimpton R, Genovesio A, Gonzalo-Asensio JA, Puzo G, Martin C, Brosch R, Stewart GR, Gicquel B, Neyrolles O. High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. PLoS Pathog. 2010 Sep 9;6(9):e1001100.

Tanne A, Ma B, Boudou F, Tailleux L, Botella H, Badell E, Levillain F, Taylor ME, Drickamer K, Nigou J, Dobos KM, Puzo G, Vestweber D, Wild MK, Marcinko M, Sobieszczuk P, Stewart L, Lebus D, Gicquel B, Neyrolles O. A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis. J Exp Med. 2009 Sep 28;206(10):2205-20.

Dos Vultos T, Blázquez J, Rauzier J, Matic I, Gicquel B. Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis. J Bacteriol. 2006 Apr;188(8): 3159-61.