SPAETH Gérald : Institut Pasteur : Molecular Parasitology and Signalling

Unit : Département Parasitologie et Mycologie - Institut Pasteur

Institut Pasteur
Unité Parasitologie moléculaire et signalisation
25 rue du Docteur Roux
75015 PARIS

Speciality : Department IM

Director of the unit : Kenneth VERNCIK

Principal investigator :

SPAETH Gérald
Email : gerald.spaethSPAMFILTER@pasteur.fr Phone number: +33 (0)1 40 61 38 58

Composition of research team:

  • SPAETH Gérald (Chef de laboratoire, HDR)
  • PRINA Eric (CR, HDR)
  • RACHIDI Najma(CR)

5 Recent publications of the research team :

Aulner N, Danckaert A, Rouault-Hardoin E, Desrivot J, Helynck O, Commere PH, Munier-Lehmann H, Späth GF, Shorte SL, Milon G, Prina E, “High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery”, PLoS Negl Trop Dis. 2013 Apr 4;7(4):e2154. Print 2013 Apr.

Horjales S, Schmidt-Arras D, Limardo RR, Leclercq O, Obal G, Prina E, Turjanski AG, Späth GF, Buschiazzo A. Structure, “The crystal structure of the MAP kinase LmaMPK10 from Leishmania major reveals parasite-specific features and regulatory mechanisms”, 2012 Oct 10;20(10):1649-60. doi: 10.1016/j.str.2012.07.005. Epub 2012 Aug 9.

Forestier CL, Machu C, Loussert C, Pescher P, and Späth GF, “Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment and host cell wounding in the infection process”, Cell Host Microbe. 2011 Apr 21;9(4):319-30.

Pescher P, Blisnick T, Bastin P, and Späth GF, “Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation”, Cell Microbiol. 2011 Mar 23. [Epub ahead of print]

Morales MA, Watanabe R, Dacher M, Chafey P, Osorio y Fortéa J, Scott DA, Beverley SM, Ommen G, Clos J, Hem S, Lenormand P, Rousselle J, Namane A, and Späth GF,  "Phosphoproteome dynamics reveal heat shock protein complexes specific to the Leishmania donovani infectious stage", PNAS 2010,107(18):8381-6.