SANSONETTI Philippe : Institut Pasteur : Molecular Microbial Pathogenesis

Unit : Département de Biologie Cellulaire et Infection - Institut Pasteur

Institut Pasteur
Unité de Pathogénie Microbienne Moléculaire (INSERM U786)
28 rue du Docteur Roux
75724 PARIS Cedex 15

Speciality : Department IM

Director of the unit : Jean-Christophe OLIVO-MARIN

Principal investigator :

SANSONETTI Philippe
Email : philippe.sansonettiSPAMFILTER@pasteur.fr Phone number: +33 (0)1 45 68 83 42

Composition of research team :

  • SANSONETTI Philippe (PR Collège de France, HDR)
  • PARSOT Claude (CL-IP, HDR)
  • PHALIPON Armelle (CL-IP, HDR)
  • SAUVONNET Nathalie (CR-IP, HDR)
  • SPERANDIO Brice (CR2-INSERM)
  • TOURNEBIZE Régis (CR1-INSERM)
  • PEDRONT Thierry (Ingénieur-IP)

5 Recent publications of the research team :

SALGADO-PABON W, CELLI S, ARENA ET, NOTHELFER K, ROUX P, SELLGE G, FRIGIMELICA E, BOUSSO P, SANSONETTI PJ, PHALIPON A.Shigella impairs T lymphocyte dynamics in vivo.Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4458-63.

PUHAR, A., TRONCHERE, H., PAYRASTRE, B., TRAN VAN NHIEU, G., SANSONETTI, P.J.A Shigella Effector Dampens Inflammation by Regulating Epithelial Release of Danger Signal ATP through Production of the Lipid Mediator PtdIns5P. Immunity 2013,  39, 1121-1131.

PEDRON T, MULET C, DAUGA C, FRANGEUL L, CHERVAUX C, GROMPONE G, SANSONETTI PJ.A crypt-specific core microbiota resides in the mouse colon.MBio. 2012 May 22;3(3). pii: e00116-12.

KONRADT C, FRIGIMELICA E, NOTHELFER K, PUHAR A, SALGADO-PABON W, DI BARTOLO V, SCOTT-ALGARA D, RODRIGUES CD, SANSONETTI PJ, PHALIPON A.The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism.Cell Host Microbe. 2011 Apr 21;9(4):263-72.

MARTEYN B, WEST NP, BROWNING DF, COLE JA, SHAW JG, PALM F, MOUNIER J, PREVOST MC, SANSONETTI P, TANG CM.(2010). Modulation of Shigella virulence in response to available oxygen in vivo. Nature. 2010 May 20;465(7296):355-8.