Giulia MANINA : Département de Biologie Cellulaire et Infection - Institut Pasteur : Microbial Individuality and Infection

Unit : Département de Biologie Cellulaire et Infection - Institut Pasteur

G5 - Individualité Microbienne et Infection
Laboratory of Excellence Integrative Biology of Emerging Infectious Diseases (LabEx IBEID)
Département de Biologie Cellulaire et Infection
Institut Pasteur
25 Rue du Dr. Roux
75724 Paris Cedex 15 – France

Plus d'informations sur : https://research.pasteur.fr/en/team/microbial-individuality-and-infection/

Speciality : Department IM

Director of the unit : Chiara ZURZOLO

Principal investigator :

Giulia MANINA
Email : giulia.maninaSPAMFILTER@pasteur.fr Phone number: +33 (0)1 45 68 87 45

Composition of research team :

  • Giulia MANINA (CR Institut Pasteur)

5 Recent publications of the research team :

Dhar N and Manina G. (2015) Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy. Methods Mol Biol 1285:241–56.

Manina G, Dhar N, and McKinney JD. (2015) Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms. Cell Host & Microbe 17(1):32–46. 

Manina G and McKinney JD. (2013) A single-cell perspective on non-growing but metabolically active (NGMA) bacteria. Curr Top Microbiol Immunol 374:135–61.

Manina G*, Bellinzoni M*, Pasca MR*, et al. (2010) Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance. Mol Microbiol 77(5):1172–85.

Makarov V*, Manina G*, Mikusova K*, Möllmann U*, et al. (2009) Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. Science 324(5928):801–4.