CROW Yanick : UMR_S1163 : Laboratory of Neurogenetics and Neuroinflammation

Unit : INSERM UMR_S1163 - IHU Imagine - Institut des Maladies Génétiques - Université Paris Descartes

IHU Imagine - Institut des Maladies Génétiques
Bâtiment Imagine
Laboratory of Neurogenetics and Neuroinflammation
24, boulevard du Montparnasse 
75015 PARIS

Speciality : Department DGNRV

Director of the unit : Alain FISCHER

Principal investigator :

CROW Yanick
Email : yanickcrowSPAMFILTER@mac.com Phone number: +44 759 539 8159

Composition of research team :

  • CROW Yanick (CL, Lab director)

5 Recent publications of the research team :

Aicardi-Goutières syndrome and the type I interferonopathies. Crow YJ, Manel N. Nature Reviews Immunology 2015:15:429-40.

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Zhang X et al. Nature 2015;517:89-93.

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Rice GI et al. Nature Genetics 2014;46:503-9.

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study. Rice GI et al. Lancet Neurology 2013;12:1159-69.

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Rice GI et al. Nature Genetics 2012;44:1243-8.