LATOUR Sylvain : UMR_S1163 : Laboratory of Lymphocyte Activation and Susceptibility to EBV

Unit : INSERM UMR_S1163 Institut Imagine Université Paris Descartes

Institut Imagine
Equipe Activation Lymphocytaire et Susceptibilité à l'EBV
24 boulevard du Montparnasse
75015 PARIS

Speciality : Department IMMUNO

Director of the unit : Alain FISCHER

Principal investigator :

LATOUR Sylvain
Email : sylvain.latourSPAMFILTER@inserm.fr Phone number: +33 (0)1 42 75 43 03

Composition of research team :

  • LATOUR Sylvain (DR-CNRS, HDR)

5 Recent publications of the research team :

Gérart S, Sibéril S, Martin E, Lenoir C, Aguilar C, Picard C, Lantz O, Fischer A and Latour S (2013). Human iNKT and MAIT cells exhibit a PLZF-dependent pro-apoptotic propensity that is counterbalanced by XIAP. Blood. Jan 24;121(4):614-23. doi: 10.1182/blood-2012-09-456095. Epub 2012 Dec 6.

Hauck F, Randriamampita C, Martin E, Gerart S, Lambert N, Lim A, Soulier J, Maciorowski Z, Touzot F, Moshous D, Quartier P, Heritier S, Blanche S, Rieux-Laucat F, Brousse N, Callebaut I, Veillette A, Hivroz C, Fischer A, Latour S#,* and C Picard# (2012). Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency. J Allergy Clin Immunol. 2012 Nov;130(5):1144-1152.e11. doi: 10.1016/j.jaci.2012.07.029. Epub 2012 Sep 15.#These authors contributed equally; *Corresponding author. 2012

Rigaud S., Lopez-Granados E., Sibéril S., Gloire G., Lambert N, Lenoir C, Synaeve C, Stacey M, Fugger L, Stephan J-L, Fischer A, Picard C, Durandy A, Chapel H and S. Latour (2011). Human X-linked variable immunodeficiency caused a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG. Blood. Jul 14;118(2):252-61. Epub 2011 May 4.

Rigaud S, Fondaneche MC, Lambert N, Pasquier B, Mateo V, Soulas P, Galicier L, Le Deist F, Rieux-Laucat F, Revy P, Fischer A, de Saint Basile G and S. Latour (2006). XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome. Nature. 444(7115):110-4.

Pasquier B, Yin L, Fondaneche MC, Relouzat F, Bloch-Queyrat C, Lambert N, Fischer A, de Saint-Basile G and S. Latour (2005). Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product. J Exp Med. 201(5):695-701.