ANTIGNAC Corinne : UMR_S1163 : Laboratory of Hereditary Kidney Diseases

Unit : INSERM UMR_S1163 IHU Imagine - Institut des maladies génétiques Université Paris Descartes

Université Paris Descartes
IHU Imagine - Institut des Maladies Génétiques
Bâtiment Imagine
Laboratoire des Maladies Rénales Héréditaires-1
24 boulevard du Montparnasse
75015 PARIS

Speciality : Department DGNRV

Director of the unit : Alain FISCHER

Principal investigator :

ANTIGNAC Corinne
Email : corinne.antignacSPAMFILTER@inserm.fr Phone number: +33 (0)1 42 75 43 45

Composition of research team :

  • ANTIGNAC Corinne (PU-PH, HDR)
  • BOYER Olivier (PHU, HDR)
  • MOLLET Géraldine (CR1)

5 Recent publications of the research team :

Colin E, Huynh Cong E, Mollet G, Guichet A, Gribouval O, Arrondel C, Boyer O, Daniel L, Gubler MC, Ekinci Z, Tsimaratos M, Chabrol B, Boddaert N, Verloes A, Chevrollier A, Gueguen N, Desquiret-Dumas V, Ferré M, Procaccio V, Richard L, Funalot B, Moncla A, Bonneau D, Antignac C. Loss-of-function mutations in WDR73 are responsible for microcephaly and steroid-resistant nephrotic syndrome: Galloway-Mowat syndrome. Am J Hum Genet. Dec 4; 95(6):6 37-48

Tory K, Menyhárd DK, Woerner S, Nevo F, Gribouval O, Kerti A, Stráner P, Arrondel C, Cong EH, Tulassay T, Mollet G, Perczel A, Antignac C. (2014). Mutation-dependent recessive inheritance of NPHS2-associated steroid-resistant nephrotic syndrome. Nat Genet.Mar;46(3):299-304.

Boyer O, Woerner S, Yang F, Oakeley EJ, Linghu B, Gribouval O, Tête MJ, Duca JS, Klickstein L, Damask AJ, Szustakowski JD, Heibel F, Matignon M, Baudouin V, Chantrel F, Champigneulle J, Martin L, Nitschké P, Gubler MC, Johnson KJ, Chibout SD, Antignac C. (2013) LMX1B mutations cause hereditary FSGS without extrarenal involvement. J Am Soc Nephrol. 2013 Jul;24(8):1216-22.

Boyer O, Nevo F, Plaisier E, Funalot B, Gribouval O, Benoit G, Cong EH, Arrondel C, Tête MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L, Bonnardeaux A, Canaud G, Charasse C, Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D, Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C, Mollet G. (2011). INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy. N Engl J Med. Dec 22;365(25):2377-88.

Ratelade J, Arrondel C, Hamard G, Garbay S, Harvey S, Biebuyck N, Schulz H, Hastie N, Pontoglio M, Gubler MC, Antignac C, Heidet L. (2010). A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes. Hum Mol Genet. 2010 Jan 1;19(1):1-15