LANGSLEY Gordon : Institut Cochin : Laboratory of Comparative Cell Biology of Apicomplexa Parasites

Unit : INSERM UMR_S1016 CNRS UMR 8104 Institut Cochin - Université Paris Descartes

Institut Cochin
Bâtiment Gustave Roussy
27, rue du Faubourg-Saint-Jacques
75014 PARIS

Speciality : Department IM

Director of the unit : Pierre-Olivier COURAUD

Principal investigator :

Email : Phone number: +33 (0)1 40 51 65 47

Composition of research team :

  • YEAR Hélène (MCU-PH, HDR)  

5 Recent publications of the research team :

*Ezougou CN, *Ben-Rached F, Moss DK, Lin JW, Black S, Knuepfer E, Green JL, Khan SM, Mukhopadhyay A, Janse CJ, Coppens I, Yera H, Holder AA, Langsley G. Plasmodium falciparum Rab5B Is an N-Terminally Myristoylated Rab GTPase That Is Targeted to the Parasite's Plasma and Food Vacuole Membranes. PLoS One. 2014 Feb 3;9(2):e87695. doi: 10.1371/journal.pone.0087695.

Metheni M, Echebli N, Chaussepied M, Ransy C, Chéreau C, Jensen K, Glass E, Batteux F, Bouillaud F, Langsley G. The level of H(2) O(2) type oxidative stress regulates virulence of Theileria-transformed leukocytes. Cell Microbiol. 2013 Sep30. doi: 10.1111/cmi.12218.

Tomlins AM, *Ben-Rached F, Williams RA, Proto WR, Coppens I, Ruch U, Gilberger TW, Coombs GH, Mottram JC, Müller S, Langsley G. Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation. Autophagy. 2013 Aug 29;9(10). [Epub ahead of print]

Rached FB, Ndjembo-Ezougou C, Chandran S, Talabani H, Yera H, Dandavate V,Bourdoncle P, Meissner M, Tatu U, Langsley G. Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases inmalaria parasites. Biol Cell. 2012 Jan;104(1):34-47. doi: 10.1111/boc.201100081.  Epub 2011 Dec 6. PubMed PMID: 22188458;

Chaussepied M, Janski N, Baumgartner M, Lizundia R, Jensen K, Weir W, Shiels BR, Weitzman JB, Glass EJ, Werling D, Langsley G. TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility. PLoS Pathog. 2010 Nov 18;6(11):e1001197. doi: 0.1371/journal.ppat.1001197.