TRAN VAN NHIEU Guy : U1050 UMR 7241 : Intercellular Communication and Microbial infections

Unit : INSERM U1050 CNRS UMR 7241 Centre Interdisciplinaire de Recherche en Biologie -

Collège de France
INSERM U1050 CNRS UMR 7241 Centre Interdisciplinaire de Recherche en Biologie
11 place Marcelin Berthelot
75005 PARIS

Speciality : Department IM

Director of the unit : Alain PROCHIANTZ

Principal investigator :

TRAN VAN NHIEU Guy
Email : guy.tran-van-nhieuSPAMFILTER@college-de-france.fr Phone number: +33 (0)1 44 27 14 89

Composition of research team :

  • TRAN VAN NHIEU Guy (DR2-INSERM, HDR)
  • GUIGNOT Julie (CR1-INSERM, HDR) 
  • PODGLAJEN Isabelle (MCU-PH)
  • ROMERO Stéphane (CR2-INSERM)

5 Recent publications of the research team :

Tran Van Nhieu G, Liu BK, Zhang J, Pierre F, Prigent S, Sansonetti P, Erneux C, Kim JK,Suh P-G, Dupont G, Combettes L. (2013) Nature Communications. Actin-basedconfinement of calcium responses during Shigella invasion. 4:1567. doi:10.1038/ncomms2561.

Romero S, Quatela A, Bornschlögl T, Guadagnini S, Bassereau P, Tran Van Nhieu G.Filopodium retraction is controlled by adhesion to its tip. J Cell Sci. (2012) Aug 16. PMID: 22899718.

Romero, S. et al. ATP-Mediated Erk1/2 Activation Stimulates Bacterial Capture by Filopodia, which Precedes Shigella Invasion of Epithelial Cells. Cell Host Microbe 9, 508-19 (2011).

Mounier J, Popoff MR, Enninga J, Frame MC, Sansonetti PJ, Tran Van Nhieu G. (2009). TheIpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells. PLoS Pathog. 5(1) : e1000271.

Jaumouillé, V, Francetic, O, Sansonetti, P, Tran Van Nhieu, G. (2008). Cytoplasmic targeting of IpaC to the bacterial pole directs polar type III secretion in Shigella. EMBO Journal. 27 :447-457