GAUSSEM Pascale : UMR_S1140 : Innovative Therapies in Haemostasis (IThEM)

Unit : INSERM UMR_S1140 Innovations thérapeputiques en hémostase (IThEM) - Université Paris Descartes

Faculté de Pharmacie
INSERM UMR_S1140  Innovations thérapeutiques en Hémostase (IThEM)
4, avenue de l’Observatoire
75006 PARIS

Speciality : Department BCMPP

Director of the unit : Pascale GAUSSEM

Principal investigator :

GAUSSEM Pascale
Email : pascale.gaussemSPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 53 73 99 39

Composition of research team :

  • GAUSSEM Pascale (PU-PH,HDR, CL)
  • ANGLES-CANO Eduardo (DR Emérite INSERM, HDR)
  • BARUCH Dominique (DR-INSERM, HDR)
  • BOISSON-VIDAL Catherine (CR CNRS, HDR, CL adjointe)
  • CRAS Audrey (MCU-PH)   
  • DIEHL Jean-Luc (PU-PH, HDR)
  • ISRAEL-BIET Dominique (PU-PH, HDR)
  • PIDARD Dominique (CR-CNRS, HDR)
  • SAMAMA Marc (PU-PH, HDR)
  • SANCHEZ Olivier (PU-PH, HDR)
  • TIMSIT Marc-Olivier (PH, HDR)

5 Recent publications of the research team :

Couturaud F, Sanchez O, Pernod G, et al.
Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial
JAMA. 2015 Jul 7;314(1):31-40.

Pietrzyk-Nivau A, Poirault-Chassac S, Gandrille S, Derkaoui SM, Kauskot A, Letourneur D, Le Visage C, Baruch D.
Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes.
PLoS One. 2015 Aug 27;10(8).

Segaliny A, Mohamadi A, Dizier B, Lokajczyk A, Brion R, Charrier C, Boisson-Vidal C*, Heymann D*.
IL-34 promotes tumour progression and metastatic process in osteosarcoma through induction of angiogenesis and macrophage recruitment.
Int J Cancer. 2015 Jul 1;137(1):73-85 (*co-derniers auteurs).

Bedarida T, Baron S, Vibert F, Ayer A, Henrion D, Thioulouse E, Marchiol C, Beaudeux JL, Cottart CH, Nivet-Antoine V.
Resveratrol Decreases TXNIP mRNA and Protein Nuclear Expressions With an Arterial Function Improvement in Old Mice.
J Gerontol A Biol Sci Med Sci. 2015 Jun 3.

Rini B, Goddard A, Knezevic D, Maddala T, Zhou M, Aydin H, Campbell S, Elson P, Koscielny S, Lopatin M, Svedman C, Martini JF, Williams JA, Verkarre V, Radulescu C, Neuzillet Y, Hemmerlé I, Timsit MO, Tsiatis AC, Bonham M, Lebret T, Mejean A, Escudier B.
A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies.
Lancet Oncol.2015 Jun;16(6):676-85.

Plawinski L, Anglés-Cano E.
Membrane microvesicles: a circulating source for fibrinolysis, new antithrombotic messengers.
Haematologica. 2013;98:e75-6.

Smadja DM, Mauge L, Nunes H, d'Audigier C, Juvin K, Borie R, Carton Z, Bertil S, Blanchard A, Crestani B, Valeyre D, Gaussem P, Israel-Biet D.
Imbalance of circulating endothelial cells and progenitors in idiopathic pulmonary fibrosis.