TARTOUR Eric : UMR_S970 : Immunotherapy and Anti-Angiogenic Therapy in Oncology

Unit : INSERM UMR_S970 Paris Centre de Recherche Cardiovasculaire

Paris Centre de Recherche Cardiovasculaire
INSERM UMR_S970
Hôpital Européen Georges Pompidou
56 Rue Leblanc
75015 Paris

Speciality : Department IMMUNO

Director of the unit : Alain TEDGUI

Principal investigator :

TARTOUR Eric
Email : eric.tartourSPAMFILTER@egp.aphp.fr Phone number: +33 (0)1 56 09 39 42

Composition of research team :

  • TARTOUR Eric (PU-PH, HDR)
  • BADOUAL Cecile (PU-PH, HDR)
  • BELEC Laurent (PU-PH, HDR)      
  • FISCHER Anne-Marie (PU-PH, HDR)  
  • GRANIER Clémence (AHU)                 
  • HELLEY Dominique (MCU-PH, HDR)
  • MAUGE Laetitia (AHU)                   
  • OUDARD Stéphane (PU-PH, HDR)      
  • QUINTIN-COLONNA Françoise (PU, HDR)     
  • SEGUIER Sylvie (PU-PH, HDR)    
  • TAIEB Julien (PU-PH, HDR)      
  • TANCHOT Corinne ( CR1, HDR)  

5 Recent publications of the research team :

VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. : Voron T, Colussi O, Marcheteau E, Pernot S, Nizard M, Pointet AL, Latreche S, Bergaya S, Benhamouda N, Tanchot C, Stockmann C, Combe P, Berger A, Zinzindohoue F, Yagita H, Tartour E, Taieb J, Terme M. J Exp Med. 2015 Feb 9;212(2):139-48. doi: 10.1084/jem.20140559

Resident Memory T Cells as Surrogate Markers of the Efficacy of Cancer Vaccines. Nizard M, Roussel H, Tartour E. Clin Cancer Res. 2015 Nov 5. [Epub ahead of print]

F.Sandoval, M. Terme, M. Nizard, C. Badoual, M.F. Bureau, L. Freyburger, O. Clement, E. Marcheteau, A. Gey, G. Fraisse, C. Bouguin, N. Merillon, E. Dransart , T Tran, F. Quintin-Colonna, G. Autret, M. Thiebaud, M. Suleman, S. Riffault, T.C. Wu , O. Launay, C Danel, J. Taieb, J. Richardson, L. Zitvogel, W.H. Fridman , L. Johannes, E.Tartour (13 feb 2013). Mucosal imprinting of vaccine induced-CD8+T cells is crucial to inhibit the growth of mucosal tumors. Sci Transl Med 5(172):172ra20

Terme M, Pernot S, Marcheteau E, Sandoval F, Benhamouda N, Colussi O, Dubreuil O, Carpentier AF, Tartour E, and Taieb J. (2013) VEGFA-VEGF Receptor pathway blockade inhibits tumor-induced regulatory T cell proliferation in colorectal cancer. Cancer Res. 73 :539-549.

 

Badoual C, Hans S, Merillon N, Van Ryswick C, Ravel P, Benhamouda N, Levionnois E, Nizard M, Si Mohamed A, N Besnier, A Gey, Rotem-Yehudar R, Pere H, Tran T, Guerin CL, Chauvat A, Dransart E, Alanio C, Albert S, Barry B, Sandoval F, Quintin-Colonna F, Bruneval P, Fridman WH, Lemoine FM, Oudard S, Johannes L, Olive D, Brasnu D, Tartour E. PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer. Cancer Res. 73 (1):128-138 .