ROGGE Lars : Institut Pasteur : Immunoregulation Unit (CNRS URA 1961)

Unit : Département d'Immunologie - Institut Pasteur

Institut Pasteur
Unité d'Immunorégulation (CNRS URA1961)
25 rue du Docteur Roux
75015 PARIS

Speciality : Department IMMUNO

Director of the unit : Mattew ALBERT

Principal investigator :

ROGGE Lars
Email : lars.roggeSPAMFILTER@pasteur.fr Phone number: +33 (0)1 40 61 38 22

Composition of research team :

  • ROGGE Lars  (CL-IP, HDR)  
  • BIANCHI Elisabetta  (CR-IP)
  • YAHIA Hanane (I-IP)

5 Recent publications of the research team :

Duffy D, Rouilly V, Libri V, Hasan M, Beitz B, David M, Urrutia A, Bisiaux A, LaBrie S, Dubois A, Delval C, Thomas S, Rogge L, Schmolz M, Quintana-Murci L, Albert M, for The Milieu Intérieur Consortium. Immunity.(2014 in press). Defining the boundaries of a healthy immune response: functional analysis of immune responsiveness using standardized whole blood stimulation systems.

Dong S, Maiella S, Xhaard A, Pang Y, Wenandy L, Larghero J, Becavin C, Benecke A, Bianchi E, Socié G, Rogge L. (2013 Sep). Multi-parameter single-cell profiling of human CD4+FOXP3+ regulatory T cell populations in homeostatic conditions and during graft-versus-host disease. Blood. 2013 Sep 5;122(10):1802-12.[See also Commentary by Koreth and Ritz, “Tregs, HSCT, and acute GVHD: up close and personal”, Blood. 5;122(10):1690-1]

Coffre M, Roumier M, Rybczynska M, Sechet E, Law H, Gossec L, Dougados M, Bianchi E, Rogge L (2013 June). Combinatorial control of Th17 and Th1 cell function by genetic variation at genes associated with the IL-23 signaling pathway in spondyloarthritis. Arthritis Rheum. 65(6):1510-21. [See also “Research Highlight” in Nature Review Rheumatology, doi:10.1038/nrrheum.2013.55]

Weiss L, Letimier FA, Carriere M, Maiella S, Donkova-Petrini V, Targat B, Benecke A, Rogge L*, Levy Y*. (2010 June). In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients.[* Equal contribution]. Proc Natl Acad Sci U S A. 8;107(23):10632-7.

Placek K, Gasparian S, Coffre M, Maiella S, Sechet E, Bianchi E, Rogge L.(2009 Dec). Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells. J Immunol. 15;183(12):7743-51.