MONTEIRO Renato : UMR1149 ERL8252 : Immunoreceptors and renal immunopathology

Unit : INSERM UMR1149 CRNS ERL8252 - Centre de Recherche sur l'Inflammation (CRI) Université Paris Diderot

Centre de Recherche sur l'Inflammation CRI
Faculté de Médecine Xavier Bichat
16 rue Henri Huchard
75018 PARIS

Speciality : Department IMMUNO

Director of the unit : Renato MONTEIRO

Principal investigator :

MONTEIRO Renato
Email : renato.monteiroSPAMFILTER@inserm.fr Phone number: +33 (0)1 57 27 77 55

Composition of research team :

  • MONTEIRO Renato (PU-PH, HDR) 
  • BERTHELOT Laureline (CR2)
  • DESCHENES Georges  (PU-PH, HDR)     
  • FLAMANT Martin (MCU-PH) 
  • KANELLOPOULOS-LANGEVIN Colette (DR2, HDR)     
  • PILLEBOUT Evangéline (PH)
  • VERBEKE Philippe (MCU, HDR) 
  • VRTOVSNIK François (PU-PH, HDR)

5 Recent publications of the research team :

Bollée G*, Flamant M*, Schordan S, Fligny C, Rumpel E, Milon M, Schordan E, Sabaa N, Vandermeersch S, Galaup A, Rodenas A, Casal I, Sunnarborg SW, Salant DJ, Kopp JB, Threadgill DW, Quaggin SE, Dussaule JC, Germain S, Mesnard L, Endlich K, Boucheix C, Belenfant X, Callard P, Endlich N, Tharaux PL. Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nat Med, 2011 Sep 25;17(10):1242-50. (*co-first authors) (IF=25.43)

Coulon S, Dussiot M, Grapton D, Maciel TT, Wang PHM, Callens C, Tiwari MK, Agarwal S, Fricot A, Vandekerckhove J, Tamouza H, Zermati Y, Ribeil JA, Djedaini K, Oruc Z, Pascal V, Courtois G, Arnulf B, Alyanakian MA, Mayeux P, Leanderson T, Benhamou M, Cogné M, Monteiro RC*, Hermine O*, Moura IC*. Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia. Nat Med, 2011 Oct 23;17(11):1456-65. (*co-senior authors) (IF=25.43)

Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PHM, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtovsnik F, Flamant M, Benhamou M, Cogné M, Moura IC, Monteiro RC. Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. J Exp Med, 2012. 209(4):793-806. (IF=14.776)

Aloulou M, Ben Mkaddem S, Biarnes-Pelicot M, Boussetta T, Souchet H, Rossato E, Benhamou M, Crestani B, Zhu Z, Blank U, Launay P, Monteiro RC. IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses. Blood. 2012 Mar 29;119(13):3084-96.

Diana J, Moura IC, Vaugier C, Gestin A, Tissandie E, Beaudoin L, Corthésy B, Hocini H, Lehuen A, Monteiro RC. Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice. J Immunol. 2013 Sep 1;191(5):2335-43.