ROUZIOUX Christine : EA 7327 : HIV infection : Reservoirs, viral diversity and resistance to antiviral drugs

Unit : EA 7327 "HIV infection : Reservoirs, viral diversity and resistance to antiviral drugs" Université Paris Descartes

Laboratoire de Virologie - EA 7327
Hôpital Necker
149 rue de Sèvres
75015 PARIS

Speciality : Department IM

Director of the unit : Christine ROUZIOUX

Principal investigator :

ROUZIOUX Christine
Email : christine.rouziouxSPAMFILTER@nck.aphp.fr Phone number: +33 (0)1 44 49 49 61

Composition of research team :

  • Christine ROUZIOUX (PU-PH, HDR)
  • Jean-Paul VIARD (PU-PH, HDR)
  • Véronique AVETTAND-FENOEL (MCU-PH, HDR)
  • Jade GHOSN (MCU-PH, HDR)
  • Antoine CHERET (PH)
  • Pierre Frange (PH)

5 Recent publications of the research team :

Chéret A, Nembot G, Mélard A, Lascoux C, Slama L, Miailhes P, Yeni P, Abel S, Avettand-Fenoel V, Venet A, Chaix ML, Molina JM, Katlama C, Goujard C, Tamalet C, Raffi F, Lafeuillade A, Reynes J, Ravaux I, Hoën B, Delfraissy JF, Meyer L, Rouzioux C; OPTIPRIM ANRS Study Group. Intensive five-drug antiretroviral therapy regimen versus standard triple-drug therapy during primary HIV-1 infection (OPTIPRIM-ANRS 147): a randomised, open-label, phase 3 trial. Lancet Infect Dis. 2015 Apr;15(4):387-96

Avettand-Fenoel V, Damond F, Gueudin M, Matheron S, Mélard A, Collin G, Descamps D, Chaix ML, Rouzioux C, Plantier JC; ANRS-CO5 HIV-2 and the ANRS-AC11 Quantification Working Group.New sensitive one-step real-time duplex PCR method for group A and B HIV-2 RNA load.J Clin Microbiol. 2014 Aug;52(8):3017-22

Ghosn J, Leruez-Ville M, Blanche J, Delobelle A, Beaudoux C, Mascard L, Lecuyer H, Canestri A, Landman R, Zucman D, Ponscarme D, Rami A, Viard JP, Spire B, Rouzioux C, Costagliola D, Suzan-Monti M; for the Evarist–ANRS EP 49 Study Group. HIV-1 DNA Levels in Peripheral Blood Mononuclear Cells and Cannabis Use are Associated With Intermittent HIV Shedding in Semen of Men Who Have Sex With Men on Successful Antiretroviral Regimens.Clin Infect Dis. 2014 Apr 21

Sáez-Cirión A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, Potard V, Versmisse P, Melard A, Prazuck T, Descours B, Guergnon J, Viard JP, Boufassa F, Lambotte O, Goujard C, Meyer L, Costagliola D, Venet A, Pancino G, Autran B, Rouzioux C; ANRS VISCONTI Study Group. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog. 2013 Mar;9(3):e1003211

Avettand-Fènoël V, Hocqueloux L, Jacquot S, Prazuck T, Legac E, Mélard A, Niang M, Mille C, Le Moal G, Viard JP, Rouzioux C; AC32 (Coordinated Action on HIV Reservoirs) of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS). Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. J Antimicrob Chemother. 2013 May;68(5):1169-78