GHIGO Jean-Marc : Institut Pasteur : Genetics of Biofilms

Unit : Département de Microbiologie - Institut Pasteur

Institut Pasteur
Unité de Génétique des Biofilms
28 rue du Docteur Roux
75724 PARIS Cedex 15

Site Web : https://research.pasteur.fr/en/team/genetics-of-biofilms/

Speciality : Department IM

Director of the unit : Hilde de REUSE

Principal investigator :

GHIGO Jean-Marc
Email : jmghigoSPAMFILTER@pasteur.fr Phone number: +33 (0)1 40 61 34 18

Composition of research team :

  • GHIGO Jean-Marc  (CL-IP, HDR)
  • BELOIN Sylvie (CL-IP,HDR)  
  • LETOFFE Christophe (Ingénieur-IP)
  • AUDRAIN Bianca (Ingénieur-IP)

5 Recent publications of the research team :

Chalabaev S, Chauhan A, Novikov A, Iyer P, Szczesny M, Beloin C, Caroff M, Ghigo JM (2014) Biofilms formed by Gram-negative bacteria undergo increased lipid A palmitoylation enhancing in vivo survival. mBio Aug. 19;5(4). pii: e01116-01114.

Lebeaux D, Chauhan A, Létoffé S, Fischer F, de Reuse H, Beloin C, Ghigo JM (2014) pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms. J Infect Dis Nov. 1;210(9):1357-1366.

Bernier S, Lebeaux D, DeFrancesco A, Valomon A, Soubigou G,, Coppee JY, Ghigo JM, Beloin C (2013). Starvation, together with the SOS response mediates high and biofilm-specific tolerance to the fluoroquinolone ofloxacin. PLoS Genet Jan. 9(1):e1003144.

Rendueles O, Ferrieres L, Fretaud M, Begaud E, Herbomel P, Levraud JP, Ghigo JM (2012) A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria. PLoS Pathog Jul. 8(7):e1002815.

Bernier, S, Létoffé, S, Delepierre, Ghigo, JM (2011). Biogenic ammonia modifies antibiotic resistance at distance in physically separated bacteria. Mol. Microbiol. 81:705-716.