PARADIS Valérie : UMR_S1149 ERL 8252 : From inflammation to cancer in digestive diseases

Unit : INSERM UMR_S1149 CNRS ERL8252 - Centre de Recherche sur l'Inflammation (CRI) Université Paris Diderot

Centre de Recherche sur l'Inflammation (CRI)
Equipe "De l'inflammation au cancer dans les maladies digestives"
Faculté de Médecine Xavier Bichat
16 rue Henri Huchard
75018 PARIS

Speciality : Department BCMPP

Director of the unit : Renato MONTEIRO

Principal investigator :

Email : Phone number: +33 (0)1 49 87 54 63

Composition of research team :

  • PARADIS Valérie (PUPH, HDR)
  • BEDOSSA Pierre (PUPH, HDR)
  • CASTERA Laurent (PH, HDR)         
  • CROS Jérôme (AHU)
  • FAIVRE Sandrine (PUPH, HDR)         
  • FARGES Olivier( PUPH, HDR)  
  • GUEDJ Nathalie (MCU-PH)
  • HAMMEL Pascal (PU-PH, HDR)
  • LEBTAHI Rachida (PUPH, HDR)         
  • LEVY Philippe (PU-PH, HDR)   
  • REBOURS Vinciane (MCU-PH)
  • RUSZNIEWSKI Philippe (PU-PH, HDR)  
  • SAUVANET Alain (PU-PH, HDR)        

5 Recent publications of the research team :

Poté N, Alexandrov T, Le Faouder J, Laouirem S, Léger T, Mebarki M, Belghiti J, Camadro JM, Bedossa P, Paradis V. Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas. Hepatology 2013;58:983-94.

Paradis V, Albuquerque M, Mebarki M, Hernandez L, Zalinski S, Quentin S, Belghiti J, Soulier J, Bedossa P. Cullin7: a new gene involved in liver carcinogenesis related to metabolic syndrome. Gut 2013;62:911-9.

Rebours V, Albuquerque M, Sauvanet A, Ruszniewski P, Lévy P, Paradis V, Bedossa P, Couvelard A. Hypoxia pathways qnd cellular stress activate pancreatic stellate cells: development of an organotypic cuture model of thick slices of normal human pancreas. PlosOne 2013;

Marijon H, Dokmak S, Paradis V, Zappa M, Bieche I, Bouattour M, Raymond E, Faivre S. Epithelial-to-mesenchymal transition and acquired resistance to sunitinib in a patient with hepatocellular carcinoma. J Hepatol 2011; 54:1073-1078

Voisin T, El Firar A, Fasseu M, Rouyer-Fessard C, Descatoire V, Walker F, Paradis V, Bedossa P, Henin D, Lehy T, Laburthe M. Aberrant expression of OX1 receptors in colon cancers and liver metastasis: an openable gate to apoptosis. Cancer Res 2011; 71:3341-3351