CHAUMEIL Julie : INSERM UMR_S1016 CNRS UMR8104 Institut Cochin : Epigenetics and nuclear organization in recombination and development

Unit : INSERM UMR_S1016 CNRS UMR8104 - Institut Cochin - Université Paris Descartes

Institut Cochin
Faculté de médecine Paris Descartes
Equipe "Epigenetics and nuclear organization in recombination and development"
24 rue du Faubourg Saint Jacques
75014 PARIS

Speciality : Department DGNRV

Director of the Unit : Pierre-Olivier COURAUD

Principal investigator :

CHAUMEIL Julie
Email : julie.chaumeilSPAMFILTER@inserm.fr Phone number:

Composition of the research team :

  • CHAUMEIL Julie

5 Recent publications of the research team :

Chaumeil J, Micsinai M, Ntziachristos P, Roth DB, Aifantis I, Kluger Y, Deriano L, Skok JA (2013)RAG2 C-terminus and ATM control RAG activity to limit the number of potential translocation substrates. Nature Comm, 31;4:2231.

Chaumeil J, Micsinai M, Ntziachristos P, Deriano L, Wang JMH, Ji Y, Nora E, Rodesch MJ, Jeddeloh JA, Kluger Y, Aifantis I, Schatz DG, Skok JA (2013)Higher-order looping and nuclear organization of antigen receptor loci facilitates targeted RAG cleavage and regulated rearrangement in recombination centers. Cell Reports, 3:359-370.

Deriano L, Chaumeil J, Coussens M, Multani A, Chou YF, Alekseyenko AV, Chang S, Skok JA, Roth DB (2011)The RAG2 C terminus suppresses genomic instability and lymphomagenesis. Nature, 471:119-23.

Chaumeil J*, Waters PD*, Koina E, Gilbert C, Robinson TJ, Marshall Graves JA (2011)Evolution from XIST-independent to XIST-controlled X-Chromosome Inactivation: Epigenetic Modifications in Distantly Related Mammals. PLoS ONE, 6: e19040.    (*Co-first and co-corresponding authors)

Chaumeil J, Le Baccon P, Wutz A, Heard E (2006)A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced.Genes & Dev, 20:2223-37.