REYNAUD Claude-Agnès : UMR_S1151 UMR8253 : Development of the immune system

Unit : INSERM UMR_S1151 CNRS UMR8253 Institut Necker Enfants-Malades ( INEM) Université Paris Descartes

Institut Necker Enfants-Malades ( INEM)
Faculté de Médecine Paris Descartes - Site Broussais
Bâtiment Leriche - porte 9 - CS61431
14 Rue Maria Helena Vieira Da Silva
75993 PARIS CEDEX 14

Speciality : Department IMMUNO

Director of the unit : Xavier NASSIF

Principal investigator :

REYNAUD Claude-Agnès
Email : claude-agnes.reynaudSPAMFILTER@inserm.fr Phone number: +33 (0)1 72 60 64 48

Composition of research team :

  • REYNAUD Claude-Agnès (DRCE CNRS,HDR)       
  • WEILL Jean-Claude (Professeur émérite,HDR)    
  • BERTOCCI Barbara (CR1-INSERM,HDR)    
  • WELLER Sandra (CR1-INSERM,HDR)
  • STORCK Sébastien (MCU)

5 Recent publications of the research team :

Descatoire, M., Weller, S., Irtan, S., Feuillard, J., Storck, S., Guiochon-Mantel, A., Bouligand, J., Morali, A., Cohen, J., Jacquemin, E., Iascone, M.,  Bole-Feysot, C., Cagnard, N., Weill, J.-C. and Reynaud, C.-A. (2014). Identification of a human splenic marginal zone B-cell precursor with NOTCH2-dependent differentiation properties. J. Exp. Med., in press

Mahévas, M., Patin, P., Huetz, F., Descatoire, M., Cagnard, N., Bole-Feysot, C., Le Gallou, S., Khellaf, M., Fain, O., Boutboul, D., Galicier, L., Ebbo, M., Lambotte, O., Hamidou, M., Bierling, P., Godeau, B., Michel, M., Weill, J.-C. and Reynaud, C.-A. (2013). "B-cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells". J. Clin. Invest. 123, 432-442

Storck, S., Aoufouchi, S., Weill, J.-C. and Reynaud, C.-A. (2011). "AID and partners: for better and (not) for worse" Curr.Opin. Immunol. 23, 337-344

Dogan, I., Bertocci, B., Vilmont, V., Delbos, F., Mégret, J., Storck, S., Reynaud, C.-A. and Weill, J.-C. (2009). « Multiple layers of B cell memory with different effector functions » Nature Immunol. 10, 1292-1299

Weill, J.-C., Weller, S. and Reynaud, C.-A.(2009). «Human marginal zone B cells» Annu. Rev. Immunol. 27, 267-285 (2009)