LEGAY Claire : UMR8119 : Development and pathologies of the Neuromuscular Junctions

Unit : CNRS UMR8119 Centre de Neurophysique, Physiologie, Pathologie - Université Paris Descartes

Faculté des Sciences Fondamentales et Biomédicales
CNRS UMR8119 Centre de Neurophysique, Physiologie, Pathologie
45 rue des Saints Pères
75270 PARIS Cedex 06

Speciality : Department DGNRV

Director of the unit : Claude MEUNIER

Principal investigator :

LEGAY Claire
Email : claire.legaySPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 42 86 20 68

Composition of research team :

  • LEGAY Claire (PR, HDR)
  • KORDELI Ekaterini (CR1-CNRS, HDR)
  • STROCHLIC Laure (CR1-INSERM, HDR)
  • DOBBERTIN Alexandre (MCU)

5 Recent publications of the research team :

Strochlic L, Falk J, Sigoillot S, Bourgeois F, Delers P, Castellani V, Swain A and Legay C. Wnt4 controls the formation of vertebrate neuromuscular junction. Plos One 7, e299976 (2013).

Karmouch J, Dobbertin A, Sigoillot S and Legay C. Developmental consequences of the ColQ/MuSK interactions. Chem. Biol. Interact. (2012).

Sigoillot SM, Bourgeois F, Lambergeon M, Strochlic L and Legay C. ColQ controls postsynaptic differentiation at the neuromuscular junction. J Neurosci. 6, 13-23 (2010).

Guerra, M., Dobbertin, A. and Legay, C. Identification of cis-acting elements involved in Acetylcholinesterase RNA alternative splicing. Mol Cell Neurosci. 38, 1-14 (2008)

Cartaud, A., Strochlic, L., Guerra, M., Blanchard, B., Lambergeon, M., Krejci, E., Cartaud, J. and C. Legay MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction, J Cell Biol , (2004) 165, 505-515