Unit : INSERM UMR_S1016 CNRS UMR8104 Instittu Cochin - Université Paris Descartes

Institut Cochin
Département Infection, Immunité, Inflammation
Bâtiment Gustave Roussy 8ème étage
7 rue du Fauboug St Jacques
75014 PARIS

Speciality : Department IMMUNO

Director of the unit : Pierre-Olivier COURAUD

Principal investigator :

HOSMALIN Anne
Email : anne.hosmalinSPAMFILTER@inserm.fr	Phone number: +33 (0)1 40 51 65 06

Composition of research team :

• HOSMALIN Anne (DR1-CNRS, HDR)
• LE BON Agnès (CR1-INSERM)
• RICHARD Yolande (DR2-CNRS, HDR)

5 Recent publications of the research team :

Dutertre CA, Amraoui S, Derosa A, Jourdain JP, Vimeux L, Goguet M, Degrelle S, Feuillet V, Liovat AS, Muller-Trutwin M, Decroix N, Deveau C, Meyer L, Goujard C, Loulergue P, Launay O, Richard Y, and Hosmalin A. (2012) Pivotal role of M-DC8+ monocytes from viremic HIV-infected patients in TNFalpha over-production in response to microbial products. Blood 120:2259-2268

Hoeffel G, Ripoche AC, Matheoud D, Gannagé M, Louis S, Nascimbeni M, Escriou N, Heshmati F*, Caillat-Zucman S, Casartelli N, Schwartz O, Guillet JG*, de la Salle H, Hanau D, Hosmalin A#, and Marañon C#. (2007). Antigen cross-presentation by Plasmacytoid Dendritic Cells. Immunity 27:481-492

Badr G#, Borhis G#, Lefevre EA, Chaoul N, Deshayes F, Dessirier V, Lapree G, Tsapis A, Richard Y. (2008) BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. Blood, 111:2744-2754. (# Co-auteurs)

Marañón, C., Desoutter, J. F., Hoeffel, G., Cohen, W., Hanau, D., and Hosmalin, A. Dendritic cells cross-present HIV antigens from live as well as apoptotic infected CD4+ T lymphocytes. Proc. Natl. Acad. Sci. USA, 2004;101:6092-6097.

Le Bon A, Etchart N, Rossmann C, Ashton M, Hou S, Gewert D, Borrow P, Tough DF. (2003) Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon. Nat Immunol.4:1009-15.