FAJAC Isabelle : EA2511 : Cystic fibrosis and chronic bronchopathy : pathobiology and clinical phenotype

Unit : EA 2511 Mucoviscidose et bronchopathies chroniques : biopathologie et phénotypes cliniques

EA2511  Mucoviscidose et bronchopathies chroniques : biopathologie et phénotypes cliniques
Faculté de médecine Paris Descartes – Site Cochin
24 rue du faubourg Saint Jacques
75014 PARIS

Speciality : Department BCMPP

Director of the unit : Isabelle FAJAC

Principal investigator :

FAJAC Isabelle
Email : isabelle.fajacSPAMFILTER@parisdescartes.fr Phone number: +33 (0)1 44 41 23 30

Composition of research team :

  • FAJAC Isabelle (PUPH, HDR)
  • ADRIE Christophe (MCU-PH, HDR)
  • BURGEL Pierre-Régis (PUPH, HDR)
  • DELCLAUX Christophe (PUPH, HDR)
  • DINH-XUAN Anh Tuan (PUPH, HDR)
  • DUSSER Daniel (PUPH, HDR)
  • PAUGAM André (MCUPH, HDR)
  • REVEL Marie-Pierre (MCUPH, HDR)
  • ROCHE Nicolas (PUPH, HDR)

5 Recent publications of the research team :

MARTIN C, COOLEN N, WU Y, THEVENOT G, TOUQUI L, PRULIERE-ESCABASSE V, PAPON J, COSTE A, ESCUDIER E, DUSSER D, FAJAC I, BURGEL PR.  (2013). CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium. Eur Respir J ;42: 1553-62. PMID: 23520314

BIENVENU T, SERMET-GAUDELUS I, BURGEL PR, HUBERT D, CRESTANI B, BASSINET L, DUSSER D, FAJAC I. (2010). CFTR channel dysfunction in non-cystic fibrosis bronchiectasis. Am J Respir Crit Care Med ;181: 1078-84. PMID: 20167849

HUBERT D, AUBOURG F, FAUROUX B, TRINQUART L, SERMET I, LENOIR G, CLÉMENT A, DINH-XUAN A-T, LOUIS B, MAHUT B, DELCLAUX C. (2009).  Exhaled NO in cystic fibrosis: relationships with airway and lung vascular impairment. Eur Respir J ; 34: 117-24. PMID: 19213782

DUONG-QUY S, DAO P, HUA-HUY T, GUILLUY C, PACAUD P, DINH-XUAN AT. (2011). Increased Rho-kinases ex-pression and activity and pulmonary endothelial dysfunction in smokers with normal lung function. Eur Respir J; 37: 349–355. PMID: 20530044

ROCHE N, DESLEE G, CAILLAUD D, BRINCHAULT G, COURT-FORTUNE I, NESME-MEYER P, SURPAS P, ESCAMILLA R, PEREZ T, CHANEZ P, PINET C, JEBRAK G, PAILLASSEUR JL, BURGEL PR. (2014 Feb).  INITIATIVES BPCO Scientific Committee. Impact of gender on COPD expression in a real-life cohort. Respir Res 17;15:20. doi: 10.1186/1465-9921-15-20. PMID: 24533770