HIVROZ Claire : UMR_S932 : Crosstalk between T lymphocytes and dendritic cells

Unit : INSERM UMR_S932 "Immunité et Cancer" Institut Curie/Université Paris Descartes

INSERM U932
Institut Curie, Section Recherche
Pavillon Pasteur
26 rue d'ULM
75248 PARIS Cedex 05

 

Speciality : Department IMMUNO

Director of the unit : Sebastian AMIGORENA

Principal investigator :

HIVROZ Claire
Email : claire.hivrozSPAMFILTER@curie.fr Phone number: +33 (0)1 56 24 68 35

Composition of research team :

  • HIVROZ Claire (DR2-INSERM, HDR)   
  • ARDOUI-BATAILLE Laurence (CR1-INSERM)

5 Recent publications of the research team :

VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites. Larghi P, Williamson DJ, Carpier JM, Dogniaux S, Chemin K, Bohineust A, Danglot L, Gaus K, Galli T, Hivroz C. Nat Immunol. 2013 Jul;14(7):723-31.

Cytokine secretion by CD4+ T cells at the immunological synapse requires Cdc42-dependent local actin remodeling but not microtubule organizing center polarity. Chemin K, Bohineust A, Dogniaux S, Tourret M, Guégan S, Miro F, Hivroz C. J Immunol. 2012 Sep 1;189(5):2159-68. Selected by F1000 .

Force generation upon T cell receptor engagement. Husson J, Chemin K, Bohineust A, Hivroz C*, Henry N*. PLoS One. 2011 May 10;6(5):e19680.* Co-corresponding author. Selected by F1000 .

T cell polarity at the immunological synapse is required for CD154-dependent IL-12 secretion by dendritic cells. Tourret M, Guégan S, Chemin K, Dogniaux S, Miro F, Bohineust A, Hivroz C. J Immunol. 2010 Dec 1;185(11):6809-18.

ZAP70: a master regulator of adaptive immunity. Fischer A, Picard C, Chemin K, Dogniaux S, le Deist F, Hivroz C. Semin Immunopathol. 2010 Jun;32(2):107-16.