ESPELI Olivier : CIRB - U1050 UMR 7241 Collège de France : Cell cycle and chromosome dynamics

Research Unit : Centre Interdisciplinaire de Recherche en Biologie (CIRB) INSERMU1050 et CNRS 7241 - Collège de France

Centre Interdisciplinaire de recherche en Biologie (CIRB)
Equipe Cycle Cellulaire et Dynamique des Chromosomes
Collège de France
11 place Marcelin Berthelot
75005 PARIS

Speciality : Department IM

Director of the Unit : PROCHIANTZ Alain

Princiapal Investigator :

ESPELI Olivier
Email : Phone number: 01 44 27 12 49

Composition of the research team :

  • ESPELI Olivier (DR - CL, HDR)
  • RIMSKY Sylvie (DR)
  • DEMARRE Gaëlle (MC, Collège de France)

5 recent publications of the team :

Hafez el Sayyed, Ludovic le Chat, Estelle Mignot, Elise Vickridge, Carine Pages, Francois Cornet, Marco Cosentino Lagomarsino and Olivier Espéli*. Mapping Topoisomerase IV binding and activity sites on the E. coli genome. PLoS Genetics, 2016 May 12;12(5):e1006025 doi: 10.1371/journal.pgen.100602

Junier I, Boccard F and ESPELI O* (2014) Polymer modeling of the E. coli genome reveals the involvement of locus positioning and macrodomain structuring for the control of chromosome conformation and segregation. Nucleic Acids Res. 42 (3), 1461-1473 2014 doi: 10.1093/nar/gkt1005

Lesterlin C, Gigant E, Boccard F, ESPELI O*, (2012) Sister chromatid interactions in bacteria revealed by a site specific recombination assay EMBO J, August 15. 31:3468-79. doi: 10.1038/emboj.2012.194.

ESPELI O*, Borne R, Dupaigne P, Thiel A, Gigant E, Mercier R, Boccard F* (2012) A MatP-divisome interaction coordinates chromosome segregation with cell division in E. coli. EMBO J  May 11. 31:3198-11. doi: 10.1038/emboj.2012.128.

Mercier R, Petit MA, Schbath S, Robin S, El Karoui M, Boccard F*, Espeli O* (2008) The MatP/matS site-specific system organizes the terminus region of the E. coli chromosome into a macrodomain. Cell 135(3): 475-485.