TEILLAUD Jean-Luc : UMR_S1138 : Cancer, Immune control, and Escape

Unit : INSERM UMR_S1138 - Centre de Recherche des Cordeliers - Univerité Pierre et Marie Curie et Université Paris Descartes

Centre de Recherche des Cordeliers
15 rue de l'école de médecine
75231 PARIS Cedex 06

Speciality : Department IMMUNO

Director of the unit : Pascal FERRE

Principal investigator :

Email : jean-luc.teilaudSPAMFILTER@crc.jussieu.fr Phone number: +33 (0)1 44 27 90 84

Composition of research team :

  • TEILLAUD Jean-Luc (DR1-INSERM, HDR)    
  • DAMOTTE Diane (PU-PH, HDR) 
  • DE REYNIES Aurélien (CL, HDR)      
  • FRIDMAN Wolf-Herman (PU-PH, HDR)     
  • SIBERIL Sophie (MCU)

5 Recent publications of the research team :

Beuselinck, B., Job, S., Becht, E., Karadimou, A., Verkarre, V., Couchy, G., Giraldo, N., Rioux-Leclercq, N, Molinié, V., Sibony, M., Elaidi, R., Teghom, C., Patard, J.J., Méjean, A., Fridman, W.H., Sautès-Fridman, C., de Reyniès A., Oudard, S.M., and Zucman-Rossi, J. Molecular subtypes of clear cell renal cell carcinoma are associated to sunitinib response in the metastatic setting. Clin. Cancer Res., 2015,

Deligne, C., Metidji, A., Fridman W.-H., and Teillaud, J.-L. Anti-CD20 therapy induces a memory Th1 response through the IFN-γ/IL-12 axis and prevents protumor regulatory T-cell expansion in mice. Leukemia, 2015, 29: 947-57.

Germain, C., Gnjatic, S., Tamzalit, F., Knockaert, S., Remark, R., Goc, J., Lepelley, A., Becht, E., Katsahian, S., Bizouard, G., Validire, P., Damotte, D., Alifano, M., Magdelenat, P., Cremer, I., Teillaud, J.-L., Fridman, W.H., Sautès-Fridman, C., and Dieu-Nosjean, M.-C. Presence of B Cells in Tertiary Lymphoid Structures is Associated with a Protective Immunity in Lung Cancer Patients. Am. J. Respir. Crit. Care Med., 2014, 189: 832-44.

Remark, R., Alifano, M., Cremer, I., Lupo, A., Dieu-Nosjean, M.C., Riquet, M., Crozet, L., Ouakrim, H., Goc, J., Cazes, A., Fléjou JF, Gibault L, Verkarre, V, Régnard, JF, Pagès, O.N., Oudard, S., Mlecnik, B., Sautès-Fridman, C., Fridman, W.H., and Damotte D. Characteristics and clinical impacts of the immune environments in colorectal and renal cell carcinoma lung metastases: influence of tumor origin. Clin. Cancer Res., 2013, 19: 4079-91.

Fridman, W.H., Pagès, F., Sautès-Fridman, C., and Galon, J. The immune contexture in human tumours: impact on clinical outcome. Nat. Rev. Cancer., 2012, 12: 298-306.